210 likes | 504 Views
II. CELL DIVISION. centrioles. spindle fibers. Chromatin. DNA double helix. DNA and histones. Supercoiled DNA. centrosome. nucleus with DNA. During Interphase , cells prepare for division Grow Replicate DNA Cell functions Mitosis = Cell Division portion of cell cycle
E N D
centrioles spindle fibers Chromatin DNA doublehelix DNA andhistones SupercoiledDNA centrosome nucleus with DNA • During Interphase, cells prepare for division • Grow • Replicate DNA • Cell functions • Mitosis = Cell Division portion of cell cycle • Must prepare DNA first • DNA wraps around proteins to condense it • Forms chromosomes • 2 copies of 9ft of DNA to pack up and separate! Chromosome
c) Chromosome structure: chromatid Original DNA Copied DNA centromere DUPLICATED CHROMOSOME (+ copied DNA) CHROMOSOME (condensed DNA) SISTER CHROMATIDS
Human Karyotype One from Dad One from Dad One from Dad One from Dad One from Dad One from Mom One from Mom One from Mom One from Mom One from Mom MALE OR FEMALE? #1-22 = Autosomal Chromosomes #23 = Sex Chromosomes
What’s different about this karyotype? MALE OR FEMALE? One from Dad One from Mom Duplicated Chromosomes
DUPLICATED OR UNDUPLICATED CHROMOSOMES? MALE OR FEMALE? WHAT’S DIFFERENT ABOUT THIS KARYOTYPE?
DUPLICATED OR UNDUPLICATED CHROMOSOMES? MALE OR FEMALE? WHAT’S DIFFERENT ABOUT THIS KARYOTYPE?
B. Mitosis (contin) • Occurs in all body cells • not reproductive cells • One cell divides into TWO identical cells • Each having 2 sets of 23 chromosomes One set from… Mom One from Dad
4. Mitosis occurs in Phases: • Prophase • Metaphase • Anaphase • Telophase To remember the order, Think of an acronym….
centrioles spindle fibers nucleus with DNA centrosome Review…. • Prior to Mitosis, what part of the CELL CYCLE is the cell in? • What is happening during this stage? Prior to Mitosis: Interphase
a) Prophase • Chromosomes become visible • (DNA condenses) • Nuclear membrane breaks down and disappears • Centrioles separate and move to opposite ends of the cell • Spindle fibersdevelop from the centrioles • Chromosomes begin to attach to spindle fibers • Longest stage of mitosis
b) Metaphase • Chromosomes complete attachment to the spindle fibers at the centromere • Chromosomes line up at the center of the cell
c) Anaphase • Cell elongates • Sister chromatids split at the centromere • Chromatids are pulled to opposite ends of the cell by spindle fibers • Shortest phase of mitosis • One set of single stranded chromosomes at each end of the cell
d) Telophase • Final stage in Mitosis • Cell membrane begins to pinch in the middle • Nuclear membranes begin to form around each group of chromosomes at each end of the cell • Chromosomes no longer visible (DNA = Chromatin) • Spindle fibers break apart
C. Cytokinesis • Separates cytoplasm and organelles • Cell divides • Results in two identical daughter cells • Differs in plants and animals: • Animals: membrane pinches in • Plants: must form cell plate first
InterphaseProphase Metaphase Anaphase Telophase Animation 1 Animation 2 Microscopic Time-lapsed Video