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Echemi Chemical METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE Description

CAS No:37088-66-7<br>Formula:C10H13NO2<br>Synonyms:METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE;(S)-3-Amino-3-phenylpropionic acid methyl ester;Methyl (S)-3-amino-3-phenylpropanoate;Benzenepropanoic acid, u03b2-amino-, methyl ester, (u03b2S)-<br>China Export:From 2018.11 to 2019.11, total export volume of METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE from China was 104,569,403KG while total export value was $249,619,259. The biggest proportion of exporting volume in the last 12 months was 10.70% in 2019.07.

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Echemi Chemical METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE Description

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  1. CAS No:37088-66-7 Formula:C10H13NO2 Synonyms:METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE;(S)-3-Amino-3-phenylpropionic acid β -amino-, methyl ester;Methyl (S)-3-amino-3-phenylpropanoate;Benzenepropanoic acid, methyl ester, (βS)- China Export:From 2018.11 to (3S)-3-AMINO-3-PHENYLPROPANOATE from China was 104,569,403KG while total export value was $249,619,259. The biggest proportion of exporting volume in the last 12 months was 10.70% in 2019.07. 2019.11, total export volume of METHYL Echemi Chemical METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE Description Pale Yellow Low Melting Solid Echemi Chemical METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE Basic Attributes CAS No：37088-66-7 Molecular Formula ：C10H13NO2 Molecular Mass ：179.22 Exact Mass ：179.09500 PSA ：52.3 A^2 LogP ：1.2 InChIKeys ：XKIOBYHZFPTKCZ-VIFPVBQESA-N H-bond Acceptor ：3 H-bond Donor ：1 SP3 ：0.30 RBN ：4 Echemi Chemical METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE Characteristics Density ：1.098±0.06 g/cm3(Predicted) Storage Condition ：-20°C Freezer, Under Inert Atmosphere Echemi Chemical METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE Safety Information HS Code ：2922499990

  2. Echemi Chemical METHYL (3S)-3-AMINO-3-PHENYLPROPANOATE Production Methods Ligand (L*) R1percentyieldb percent eec config. 7 D Ph 92 96 S 8 D 4-F-Ph 62 96 S 9 D 4-OMe-Ph 88 95 S 10 D 3-Pyridyl 91 96 11 D PhCH2- 94 93 12 D 4-CF3-Ph- 94 97 S a: Reaction conditions: 0.15 molpercent [Rh(cod)Cl]2; 0.33 molpercent ligand, 50 °C, 100 psig H2. b Assay yield; c Assayed by chiral HPLC using a AS-RH or AD-RH chiral column eluting with 25-40percent acetonitrile/water as the (S)-3-tert-Butoxycarbonylamino-3-phenyl-propionic (S)-3-amino-3-phenyl-propionic acid methyl ester (2.27 g, 12.67 mmol), di-tert-butyl dicarbonate (3.68 g, 16.89 mmol), 2 N sodium hydroxide (10.5 mL) in tetrahydrofuran (20 mL) was stirred at ambient temperature for 2 hours. The mixture was partitioned between water and ethyl acetate. The organic layer was separated, dried and concentrated to give a crude residue which was passed through a short pad of silica gel to give the title compound. Yield: 2.4 g (68percent). 1H-NMR (CDCl3.) delta: 1.41 (s, 9H), 2.88 (m, 2H), 3.60 (s, 3H), 5.09 (br s, 1H), 5.49 (br s, 1H), 7.30 (m, 5H). mobile acid phase.Step ester: 2 of methyl A mixture

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