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Hepatocellular Carcinoma (HCC): Content. Burden of HCC Diagnosis of HCC Staging of HCC Treatment of HCC: - Very early / early HCC- Intermediate HCC - Advanced HCC A Look to the future . HCC: Common and Increasing. 694,000 deaths from liver cancer yearly worldwide[1] Age-adjusted US incidence has increased 2-fold from 1985-1998[2] - Expected to continue to increase until 2015-2020[3] American Cancer Society statistics for liver cancer in 2010[4] - Estimated new cases: 24,1209443

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