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zebrafish developmental toxicity assay

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zebrafish developmental toxicity assay

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  1. zebrafish developmental toxicity assay

  2. Creative Biostructure is a biotechnology company offering drug discovery contract services to pharma, biotech, chemical companies, and academic institutes. Based on our zebrafish screening platform, we can provide MagHelix™ toxicity assays using zebrafish. Zebrafish has been a prominent model vertebrate for investigating chemical toxicity. We aim at developing new and faster screen/bioassays using zebrafish as an animal model, as well as new technologies for optimizing the maintenance and breeding of zebrafish.

  3. Our MagHelix™ Toxicity Assay Services include but are not limited to:

  4. Advantages of our MagHelix™ Toxicity Assay services: • Applied for preclinical drug assessment, and the toxicity assay results are the basis for the optimization of drug candidates, which is conducive to reducing the cost of research and development. • We have a professional zebrafish screening platform for the development of disease models and in vivo drug screening. • Flexible lead compound toxicity assessment services, we also have extensive experience in computational toxicity prediction and high-throughput in vitro ADME-Tox profiling. • For each project, our team of drug discovery experts will provide an appropriate solution and actively communicate with customers. • We adopt a strict confidentiality policy for project information and experimental data.

  5. Creative Biostructure provides high-value services for any organization with a need for zebrafish model development or drug toxicity evaluation. We have the ability to provide highly efficient and customized toxicity assays to meet your requirements. References Panzica-Kelly J M.; et al. Zebrafish embryo developmental toxicology assay. Developmental Toxicology. Humana Press, Totowa, NJ. 2012: 25-50. TG236 O. OECD guidelines for the testing of chemicals section 2: Effects on biotic systems test No 236: fish embryo acute toxicity (FET) test. Organization for Economic Cooperation and Development. Paris, France, 2013. Kiper K G, Freeman J L. Zebrafish as a tool to assess developmental neurotoxicity. Cell Culture Techniques. Humana, New York, NY, 2019: 169-193.

  6. Related Services: • In Vitro ADME-Tox Profiling • MagHelix™ Zebrafish Disease Model Generation • NMR-based Pharmacometabonomics • MagHelix™ Efficacy Testing Using Zebrafish

  7. THANKS Excerpt from: https://drug-discovery.creative-biostructure.com/maghelix-toxicity-assays-using-zebrafish-p35

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