Understanding Ankylosing Spondylitis: A Guide for Patients

1. Understanding Ankylosing Spondylitis: A Guide for Patients Ankylosing Spondylitis (AS) is a chronic, inflammatory disease that primarily affects the spine and sacroiliac joints. Over time, it can lead to stiffness, pain, and in severe cases, the fusion of spinal vertebrae. While there is no cure, early diagnosis and appropriate treatment can significantly improve the quality of life. What is Ankylosing Spondylitis? Ankylosing Spondylitis is a form of arthritis that causes long-term inflammation of the spine and other areas of the body. The inflammation can lead to new bone formation, which may cause sections of the spine to fuse in a fixed, immobile position. Causes and Risk Factors Genetics: The HLA-B27 gene is strongly associated with AS. Family History: A family history of AS increases the risk. Age and Gender: AS typically begins in early adulthood (between ages 17 and 45) and is more common in men. Symptoms:- Chronic pain and stiffness in the lower back and hips. Pain that worsens in the morning or after inactivity. Fatigue Reduced flexibility of the spine Pain in other joints (shoulders, knees) In advanced cases, fusion of spinal vertebrae Diagnosis Medical History and Physical Exam : Doctors look for patterns of pain and stiffness. Imaging Tests : X-rays, MRI scans to detect changes in the sacroiliac joints and spine. Blood Tests : To check for inflammatory markers and the HLA-B27 gene. Treatment Options While AS cannot be cured, its symptoms can be managed effectively. 1.Medications: oNSAIDs (e.g., ibuprofen, naproxen) for pain and inflammation oDMARDs (for peripheral joint involvement) oBiologic agents (e.g., TNF inhibitors, IL-17 inhibitors)

2. 2.Physical Therapy: oExercises to improve posture, flexibility, and strength oBreathing exercises to maintain chest expansion 3.Lifestyle Modifications: oRegular exercise oGood posture habits oSmoking cessation (as smoking worsens symptoms) 4.Surgery: oIn rare cases, joint replacement surgery or spinal correction may be required Complications Fusion of spinal vertebrae Eye inflammation (uveitis) Reduced lung function due to rib cage involvement Cardiovascular issues Living with Ankylosing Spondylitis With appropriate management, many individuals with AS lead active and productive lives. Staying informed, adhering to treatment plans, and maintaining an active lifestyle are key to managing the disease. When to See a Doctor Persistent back pain and stiffness, especially in the morning Pain that improves with activity but not with rest Family history of AS Vision problems, chest pain, or difficulty breathing ConclusionAnkylosing Spondylitis is a serious but manageable condition. Early diagnosis and an individualized treatment plan can help patients maintain a good quality of life. Working closely with a rheumatologist or spine specialist is essential to control inflammation and preserve mobility. Contact us:- Dr. Sarthak Kadakia | Best Spine Surgeon in Borivali | Spine Specialist in Mumbai Contact :9701549701 E-mail : https://maps.app.goo.gl/bCGfZvTAKWE2dJKa6