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Presenting A PICO(T) Process Findings PICO(T) Findings Dennis Sasati School of Nursing and Health Sciences, Capella University NURS-FXP4025: Improving Outcomes in Hyperemesis Gravidarum Professor Angela Wallace October 5, 2025
“Hello everyone, and thank you for joining me today.” My name is Dennis Sasati, and I’ll be presenting my evidence-based project titled: “Improving Outcomes in Hyperemesis Gravidarum Through Early Nurse-Led Interventions.” This presentation explores how early, structured, nurse-led care can significantly reduce complications associated with hyperemesis gravidarum, or HG.
1. Diagnosis Overview: What is Hyperemesis Gravidarum? Hyperemesis Gravidarum is not your typical morning sickness. It’s a severe, persistent form of nausea and vomiting during pregnancy, often resulting in: Dehydration Electrolyte imbalance Significant weight loss Malnutrition And in some cases, even hospitalization or more severe complications. While it usually appears during the first trimester, symptoms can persist throughout the pregnancy. Emerging evidence also links unmanaged HG with serious neurological conditions. For example, Magdalena et al. (2025) documented cases of optic nerve neuropathy in HG patients with Wernicke’s Encephalopathy, a life- threatening brain disorder caused by vitamin B1 deficiency. This underlines the urgency of early nursing intervention to prevent irreversible damage.
2. My PICO(T) Question Using the PICO(T) framework, I asked: In pregnant women with hyperemesis gravidarum, how does early nurse-led intervention compared to standard or delayed care impact hospitalization rates and symptom control within the first trimester? This question helped guide a focused literature review around nursing-led protocols, early diagnosis, and digital follow-up interventions.
3. Summary of Evidence Let me briefly highlight three key sources: Abo Elmagd & Muna (2024) conducted a cross-sectional study showing that nursing students, when properly trained, are highly motivated and willing to apply evidence-based practices in clinical settings. This suggests that nurse-led protocols for HG are both feasible and scalable. Auger et al. (2024) followed children born to mothers with HG and found increased risks for respiratory issues and developmental delays. This long-term view reinforces the need for early interventions to reduce maternal- fetal risk. Magdalena et al. (2025) explored the use of optical coherence tomography to diagnose optic nerve neuropathy caused by HG-related nutrient deficiency. Their findings show that delayed treatment can result in permanent neurological damage—making early detection and care vital. Each of these articles is peer-reviewed, current, and directly supports early nursing involvement in managing HG.
3. Summary of Evidence Let me briefly highlight three key sources: Abo Elmagd & Muna (2024) conducted a cross-sectional study showing that nursing students, when properly trained, are highly motivated and willing to apply evidence-based practices in clinical settings. This suggests that nurse-led protocols for HG are both feasible and scalable. Auger et al. (2024) followed children born to mothers with HG and found increased risks for respiratory issues and developmental delays. This long-term view reinforces the need for early interventions to reduce maternal- fetal risk. Magdalena et al. (2025) explored the use of optical coherence tomography to diagnose optic nerve neuropathy caused by HG-related nutrient deficiency. Their findings show that delayed treatment can result in permanent neurological damage—making early detection and care vital. Each of these articles is peer-reviewed, current, and directly supports early nursing involvement in managing HG.
Recommended Key Steps of Care: Based on the research, here are five evidence-based nursing steps I recommend: Early Screening in the First Trimester – Ask specific HG-related questions at prenatal intake visits. Patient Education – Provide guidance on hydration, nutrition, rest, and red flags. Mobile Follow-Up Tools – Use texts or telehealth to track symptom severity and patient compliance. As Hinkle et al. (2025) suggested, this is especially effective for underserved populations. Nutritional and Emotional Support – Refer to dietitians and provide reassurance to reduce anxiety, which can worsen symptoms. Timely Diagnostics and Referral – Early use of lab work or imaging like ultrasound, as highlighted in Brunel et al. (2025), can confirm HG and exclude other causes.
Conclusion In conclusion: Hyperemesis Gravidarum poses significant risks if not managed promptly. Early, nurse-led interventions, including education and digital support, are not just helpful—they’re critical to improving maternal and fetal outcomes. Nurses must champion these early interventions, particularly for patients in underserved or rural areas, where access to specialized care may be limited. This project demonstrates that evidence-based nursing practices can—and should—lead the charge in tackling HG more effectively.
References: The key sources I cited include: -Abo Elmagd & Muna (2024) -Auger et al. (2024) -Magdalena et al. (2025) You’ll find full APA references listed on the poster.
“Thank you for your time. If you have any questions or would like to see the full reference list, feel free to reach out. I hope this presentation helped highlight the critical role of early nursing intervention in managing hyperemesis gravidarum.”
References Abo Elmagd Manal, H., & Muna, A. (2024). Nursing Students’ Beliefs and Willingness to Implement Evidence-Based Nursing Practice at Umm Al-Qura University: A Descriptive Cross-Sectional Study. Cureus, 16(4)https://doi.org/10.7759/cureus.58521 Auger, N., Padda, B., Bégin, P., Brousseau, É., & Côté-Corriveau, G. (2024). Hyperemesis gravidarum and the risk of offspring morbidity: a longitudinal cohort study. European Journal of Pediatrics, 183(9), 3843-3851. https://doi.org/10.1007/s00431-024-05647-8 Magdalena, K., Brzdęk Michał, Justyna, T., Szadkowski Paweł, & Zarębska-Michaluk Dorota. (2025). Swept-Source Optical Coherence Tomography in the Diagnosis and Monitoring of Optic Nerve Neuropathy in Patients with Wernicke’s Encephalopathy Due to Hyperemesis Gravidarum. Journal of Clinical Medicine, 14(11), 3849. https://doi.org/10.3390/jcm14113849
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