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This mini-grant application outlines how protein structure can illuminate the study of evolution, building on existing research in the field. Understanding the three-dimensional arrangement of proteins provides insights into evolutionary adaptations and the functional implications of genetic variations. The specific aims include investigating the correlation between protein conformations and evolutionary traits, employing advanced structural biology techniques. This proposal highlights a review of relevant literature affirming these concepts, alongside novel hypotheses that emerge from ongoing advancements in protein structure analysis.
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Assignment 4 • You are to write a mini grant application on “How Protein Structure Can Be Used to Study Evolution” • It will consist of: • an introduction as to why structure is useful to study evolution and work that has been done in the field already • Specific aims on what you will do when awarded the grant
Rubric • An understanding of what protein structure brings to the study of evolution (5) • Description of the most relevant literature and evidence that you have read and understood it (7) • Novelty of your ideas as embodied in the specific aims (8) • (Total 20)
