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Albert Hoffman discovered the psychoactive effect of LSD in the 1940s, inadvertently from a compound that was synthesised by him as a potential medicine for the company Sandoz. He readily absorbed the compound and found himself experiencing fleeting hallucinations. A Swiss chemist accidentally absorbed a chemical he synthesised, which became LSD. The psychoactive effect of LSD was first discovered in the 1940s by Dr Albert Hofmann. He absorbed it while working, and experienced a hallucination while on a bicycle ride home. LSD is often regarded as a ‘classic’ psychedelic drug. It was first discovered in 1938 by Swiss chemist Albert Hofmann, who was researching the chemical structure of seeds from different types of plants. Around a decade later, he synthesised its chemical structure and began testing its effects on animals. In 1943, he accidentally absorbed some during his research, and experienced an unusual sensation: a slight sense of unsteadiness in his body and blurred vision. Despite feeling slightly anxious, he went home for the rest of the day, having selected two other compounds for testing. Later in his office, he realised that his earlier experience was caused by LSD- 25!