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HUMAN CASES H5N1 2004-2006. Case fatality rate ~ 50%Most deaths from refractory respiratory failureMost people are critically illRespiratory failure > 70%ShockAcute renal failure 10-29%In US, pts with similar severity of illness are managed in ICUs. CRITICAL CARE DEMAND. Number of critically ill patients?? availability and effectiveness of countermeasures Uncertain virulence of strain if human-to-human transmissionRate of development of critical illnessTime from hosp to resp failure9458

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