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Apoptosis

Apoptosis

PRESENTED BY DOCTOR DEATH. Apoptosis. Learning Objectives To Die For. To understand the proteins involved in apoptosis. Know the regulation of apoptotic signaling pathways. Importance of apoptosis in the immune system and diseases. Apoptosis (Programmed cell death).

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1.55k views • 88 slides
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?????. ? 14 ? ????. ?????? ???. ???? ??? T ?????????????????????????? ????????????????????????? ITAM/ITIM ???????????????????????????????????????. ? ? ? ? ? immune regulation ?. ??????? , ?? ????????? ??????? , ?? ?? ??????? , ?????????? , ????????????????. ?????????. ????

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934 views • 62 slides
Dysfunction Apoptosis and Disease

Dysfunction Apoptosis and Disease

?????????. Dysfunction Apoptosis and Disease. ????. 1 ??? 2 ??????????? 3 ???????? 4 ??????????. (General introduction). 1. ??. 1.1 ?? ???? ( apoptosis,Apo ): ????????????? ??????? (programmed cell death ,PCD). 1.2. Apo. ???. 1. 2.1. Apo. ??????.

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628 views • 40 slides
??? A ??? ?????? ?????????? ??????? ???????

??? A ??? ?????? ?????????? ??????? ???????

The Nobel Prize in Physiology or Medicine 2002 ---- for their discoveries concerning programmed cell death. ??? A ??? ?????? ?????????? ??????? ???????. Sydney Brenner. ?? Crick ???? DNA ? RNA? ??? ???????????.

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531 views • 40 slides
The Amyloid Hypothesis of Alzheimer Pathogenesis

The Amyloid Hypothesis of Alzheimer Pathogenesis

APP. Self-assembly. Amyloid- b production. tau. neuronal cell death. clinical AD. The Amyloid Hypothesis of Alzheimer Pathogenesis. APP: Chromosomal Location. APP Genetic locus on Chr. 21q21.3. APP is a single copy gene. It exists as one copy per haploid genome.

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640 views • 31 slides
Chapter 17: Cell Death

Chapter 17: Cell Death

Chapter 17: Cell Death. Know the terminology : Apoptosis, necrosis, Bcl-2, caspase, procaspase, caspase-activated DNAse (or CAD), death domain, cytochrome c, mitochondrial permeability transition pore, Apaf, FAS, TNF a ,. The many forms of cell death. Necrosis:

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627 views • 31 slides
Mechanisms of Cell Death

Mechanisms of Cell Death

Mechanisms of Cell Death. Etiology of cell death. Major Factors Accidental Genetic Necrosis Apoptosis. Necrosis: The sum of the morphologic changes that follow cell death in a living tissue or organ Apoptosis:

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434 views • 31 slides
Cleavage of IP 3 R1 by caspase-3 and intracellular Ca 2+ homeostasis during Apoptosis

Cleavage of IP 3 R1 by caspase-3 and intracellular Ca 2+ homeostasis during Apoptosis

Cleavage of IP 3 R1 by caspase-3 and intracellular Ca 2+ homeostasis during Apoptosis. Laboratory of Physiology, KULeuven, Belgium Assefa Z, Bultynck G, Szlufcik K, Nadif Kasri N, Vermassen E, Goris J, Missiaen L, Callewaert G, Parys JB & De Smedt H. Apoptosis: brief introduction.

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Caspase Activity in Apoptotic Cells

Caspase Activity in Apoptotic Cells

Caspase Activity in Apoptotic Cells. Cell Bio 220 Tenzin Dolkar Stephanie Kim Victoire Ndong Patricia Wong. Caspases. Are families of proteases which are involved in initiating apoptotic events Synthesized in the cell as precursors-procaspase Cleave proteins at aspartic acid residue sites

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285 views • 13 slides
Fas/Fas-L and its involvement in Autoimmune Diabetes

Fas/Fas-L and its involvement in Autoimmune Diabetes

Fas/Fas-L and its involvement in Autoimmune Diabetes. BIOL537: Immunobiology Spring 2001 Brooke Martin Paul Nalliah. Apoptosis. Cysteine proteases a part of the caspase protein family are activated specifically in apoptosis

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106 views • 10 slides
H 2 O 2

H 2 O 2

OUT. IN. e -. e -. e -. e -. e -. e -. e -. e -. . OH. GPx. H 2 O 2. H 2 O 2. +. Cyt C. Cyt C. Cyt C. Fe 2+. Cat. e -. e -. O 2. O 2. O 2. O 2. O -. O -. ADP. ATP. Q. H 2 O. H 2 O. Mitochondrial Electron Transport Chain. H + H + H + H + H +. H +.

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Abstract

Abstract

Regulation of Caspase-3 by PKC ?. Sean Crisafi 1 , Yadira Malavez 4 , and Andrea Doseff 2,3

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