Protein Synthesis. A gene is the basic unit of heredity in a living organism All living things depend on genes Genes hold the information to build and maintain their cells and pass genetic traits to offspring the term gene often refers to the scientific concept of an allele .
Biochemical reactions are controlled by enzymes
Enzymes are often are organized into chains of reactions known as metabolic pathways. Loss of activity in a single enzyme can inactivate an entire pathway.
He hypothesized that a defective enzyme causes an "inborn error of metabolism“
If there is an accumulation of substance B, then enzyme 2 must be defective
If there is an accumulation of substance C, then enzyme 3 must be defective
+ Amino Acid
If the precursor accumulated, the defect was in enzyme A
If ornithine accumulated, enzyme B was defective
The while studying the amino acid sequence of hemoglobin from individuals with sickle cell anemiacentral dogma of molecular biology is the
proposition put forward by Francis Crick
The information flow in the cell goes from the
deoxynucleicacid DNA, to the ribonucleic acid
messenger RNA, to protein
Never from protein to nucleic acids.
Translation while studying the amino acid sequence of hemoglobin from individuals with sickle cell anemia