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Cutaneous Manifestations of Systemic Diseases

Cutaneous Manifestations of Systemic Diseases. Hayden H. Franks, MD June 13, 2013. Who Is This Guy?. Private practice Dermatologist Clinics in Little Rock and Texarkana Fellow of the American Academy of Dermatology Diplomat of the American Board of Dermatology

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Cutaneous Manifestations of Systemic Diseases

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  1. Cutaneous Manifestations of Systemic Diseases Hayden H. Franks, MD June 13, 2013

  2. Who Is This Guy? • Private practice Dermatologist • Clinics in Little Rock and Texarkana • Fellow of the American Academy of Dermatology • Diplomat of the American Board of Dermatology • Honorary Member of the Arkansas Academy of Family Physicians

  3. Disease Categories • Autoimmune Diseases • Endocrine Diseases • Cardiac Diseases • Pulmonary Diseases • Neurological Diseases • Infectious Diseases • Hematologic Diseases • Gastrointestinal Diseases • Diseases not otherwise specified

  4. Cutaneous Manifestations of Systemic Diseases • Frequently encountered • May be the initial sign of internal disease • May occur late in the course of the disease • May assist in making the diagnosis • May be obvious or subtle • Overlap of Family Practice and Dermatology

  5. AUTOIMMUNE DISEASES • Systemic Lupus Erythematosus • Scleroderma • Dermatomyositis • Rheumatoid Arthritis

  6. ENDOCRINE DISEASES • Diabetes Mellitus • Thyroid Disease • Adrenal Disease

  7. CARDIAC DISEASES • Congestive Heart Failure • Hypertension

  8. PULMONARY DISEASES • Sarcoidosis • Tuberculosis • Scleroderma • Blastomycosis

  9. GASTROINTESTINAL DISEASES • Inflammatory Bowel Disease • Celiac Disease • Hepatitis

  10. NEUROLOGICAL DISEASES • Neurofibromatosis • Tuberous Sclerosis • Parkinson’s Disease

  11. INFECTIOUS DISEASES • HIV • Tuberculosis • Blastomycosis

  12. HEMATOLOGIC DISEASES • Expressed in a limited number of ways • Extravasation of whole blood • Infiltration by migrating blood cells • Changes in color or pigmentation • Ulceration

  13. Ulceration • Self inflicted excoriations from intense pruritus • Hodgkin’s Disease, PCV, Cutaneous Lymphomas • Sickle Cell Disease

  14. Blood Extravasation • Thrombocytopenia • Defects in Platelet Function • Purpura • Easy or spontaneous bruising • Petechiae • Senile Purpura (Bateman’s Purpura)

  15. Change in Color and Pigmentation of the Skin • Progressive Pigmentary Purpura (Schamburg’s Purpura) • Anemia • Cyanosis

  16. Cutaneous Manifestations of Gastrointestinal Diseases • Jaundice • Melanosis • Nail Changes • Edema • Purpura • Pruritus • Vascular Changes • Spider Telangiectasias • Palmar Erythema

  17. Cutaneous Manifestations of Hepatitis • Urticaria • Vasculitis • Polyarteritis Nodosa • Relapsing Papulovesicular Rash

  18. DERMATITIS HERPETIFORMIS

  19. Cutaneous Manifestations of Ulcerative Colitis and Crohn’s Disease • Pyoderma Gangrenosum • Erythema Nodosum • Aphthous Ulcers • Lichen Planus

  20. DISEASES NOT OTHERWISE SPECIFIED • Sarcoidosis

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