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The Urinary System

The Urinary System. Function. Remove nitrogenous wastes Maintain electrolyte, acid-base, and fluid balance of blood Homeostatic organ Acts as blood filter Release hormones: calcitriol & erythropoietin. Kidneys as Filters. Diuretic- loose water; coffee, alcohol

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The Urinary System

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  1. The Urinary System

  2. Function • Remove nitrogenous wastes • Maintain electrolyte, acid-base, and fluid balance of blood • Homeostatic organ • Acts as blood filter • Release hormones: calcitriol & erythropoietin

  3. Kidneys as Filters • Diuretic- loose water; coffee, alcohol • Antidiuretic- retain water; ADH • Aldosterone- sodium & water reabsorption, and K+ excretion • GFR= 180 liters (50 gal) of blood/day • 178-179 liters are reabsorbed back into blood • Excrete a protein free filtrate

  4. The Urinary System Maintaining Chemical Homeostasis

  5. The Urinary System

  6. blood filtration tubular reabsorption and secretion General Functioning of the Kidney “refreshed” blood urine

  7. Nitrogenous Wastes urea uric acid ammonia

  8. kidneys ureters urinary bladder urethra Organs of the Urinary System

  9. renal pyramids renal pelvis renal cortex renal capsule ureter renal medulla Kidney Anatomy

  10. nephron renal artery renal vein Kidney Anatomy

  11. blood filtration tubular reabsorption and secretion Nephron Functioning “refreshed” blood urine

  12. glomerulus efferent arteriole Bowman’s capsule afferent arteriole proximal convoluted tubule artery distal convoluted tubule peritubular capillaries vein collecting duct loop of Henle

  13. Each kidney contains over 1 million nephrons and thousands of collecting ducts renal cortex renal medulla DCT Glomerulus PCT Collecting duct Loop of Henle

  14. efferent arteriole afferent arteriole Bowman’s capsule glomerulus Glomerular Filtration Filters blood; proteins can’t pass through

  15. Composition of Glomerular Filtrate • Water • Small Soluble Organic Molecules • Mineral Ions

  16. Proximal Convoluted Tubule Reabsorbs: water, glucose, amino acids, and sodium. • 65% of Na+ is reabsorbed • 65% of H2O is reabsorbed • 90% of filtered bicarbonate (HCO3-) • 50% of Cl- and K+

  17. Loop of Henle Creates a gradient of increasing sodium ion concentration towards the end of the loop within the interstitial fluid of the renal pyramid. • 25% Na+ is reabsorbed in the loop • 15% water is reabsorbed in the loop • 40% K is reabsorbed in the loop

  18. Distal Convoluted Tubule Under the influence of the hormone aldosterone, reabsorbs sodium and secretes potassium. Also regulates pH by secreting hydrogen ion when pH of the plasma is low. • only 10% of the filtered NaCl and 20% of water remains

  19. Collecting Duct Allows for the osmotic reabsorption of water. ADH (antidiuretic hormone)- makes collecting ducts more permeable to water-- produce concentrated urine

  20. Urine • Water- 95% • Nitrogenous waste: • urea • uric acid • creatinine • Ions: • sodium • potassium • sulfate • phosphate From the original 1800 g NaCl, only 10 g appears in the urine

  21. Hormonal Control of Kidney Function

  22. heart receptors hypothalamus Hormonal Control of Kidney Function high plasma solute concentration low blood volume

  23. posterior pituitary antidiuretic hormone collecting ducts Hormonal Control of Kidney Function hypothalamus

  24. Hormonal Control of Kidney Function

  25. INQUIRY • List several functions of the kidneys. • What does the glomerulus do? • What are several constitutes you should not find in urine? • What is specific gravity? • What two hormones effect fluid volume and sodium concentration in the urine? • Where are the pyramids located in the kidney? • What vessel directs blood into the glomerulus? • Where does most selective reabsorption occur in the nephron?

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