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Pathology quiz

Pathology quiz . Week 31 MSK. Osteoarthritis Severe at the hip erosion of cartilage cyst formation osteophyte. Scoliosis Secondary to OA the vertebrae and/or discs on one side of the spine weaken or degenerate more than those on the other side, creating a curve Disc degeneration

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Pathology quiz

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  1. Pathology quiz Week 31 MSK

  2. Osteoarthritis • Severe at the hip • erosion of cartilage • cyst formation • osteophyte

  3. Scoliosis • Secondary to OA • the vertebrae and/or discs on one side of the spine weaken or degenerate more than those on the other side, creating a curve • Disc degeneration • ostephytes

  4. OA • Severe kyphosis • Degeneration of discs • Anterior ostephytes • Schmorl’s nodes • protrusions of disc material into the surface of the vertebral body

  5. Chronic RA • Fibrous tissue surround the knee joint

  6. Chronic RA • Marked osteoporosis in both joints • Dislocation of knee joint • Ankylosis of hip joint • Thinning of cortex of bone • Marrow hyperplasia in femur due to hypersplenism and long term glucocorticoid therapy.

  7. Osteoporosis - Gross reducation in number and size trabeculae

  8. RA • Thickened and hyperplasticsynovium • hyperplasticsynoviocytes (blue) • Chronic inflammation (red)

  9. RA • Rheumatoid nodule • From elbow of 66 yo man • Present in 20% of RA patients, usually with more aggressive form of RA. • Palisadingepitheloid cells • Fibroblasts and macrophages • pink amorpheus fibrin staining center – degenerated collagen

  10. Chronic tophaceousgout

  11. OA • 50 yo patient with haemophilia • Hx of hemoarthrosis • haemosiderosis of the synovium • Erosion of cartilage

  12. Gout • Aggregates of urate crystals surrounded • by foreign body giant cells • Needle-shaped urate crystals

  13. Gout • First metatarso-phalangealjoints • urate is deposited both within joints and extra articular tissue

  14. Severe ankylosingspondylitis • Fracture of cervical spine from fall • Compression and necrosis of cervical cord • Ossified longitudinal ligaments • Replaced intervertebral discs

  15. Septic arthritis • in head of humerus • S.aureus • Destruction of articular surface

  16. Septic arthritis TB • Compression of spinal cord

  17. HPO • Hypertropic pulmonary osteoarthropathy • new bone formation under the periosteum • Malignant pleural mesothelioma

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