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Gametogeneza Originea celulelor germinale GAMETI ECTODERM

Gametogeneza Originea celulelor germinale GAMETI ECTODERM POPULATIE CELULARA – LINIE GERMINALA – MIGREAZA PERETII SACULUI VITELIN – ENDODERM Mezoul primitiv dorsal al tubului digestiv PERETELE DORSAL AL TRUNCHIULUI GONADA PRIMITIVA – T 10 ANOMALII – DE MIGRARE

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Gametogeneza Originea celulelor germinale GAMETI ECTODERM

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  1. Gametogeneza • Originea celulelor germinale GAMETI • ECTODERM • POPULATIE CELULARA – LINIE GERMINALA – • MIGREAZA • PERETII SACULUI VITELIN – ENDODERM • Mezoul primitiv dorsal al tubului digestiv • PERETELE DORSAL AL TRUNCHIULUI • GONADA PRIMITIVA – T 10 • ANOMALII – DE MIGRARE • - TERATOAME • - INTRERUPEREA DEZVOLTARII GONADEI

  2. DEFINITIAGAMETOGENEZEI: Transformarea celulelor germinative primordiale prin MEIOZA si DIFERENTIERE CELULARA in GAMETI MATURI.

  3. Spermatogeneza - 64 de zile Celule germinative primordiale Diploide, 2N PUBERTATE MITOZE ( 16 zile ) Spermatogonia Diploid, 2N Sinteza ADN Spermatocit primar Diploid, 4N Meioza I ( 8 zile ) Spermatocit secundar Haploid, 2N Meioza II ( 16 zile ) Spermatide Haploid, 1N Spermiogeneza ( 24 de zile ) Spermatozoid adult Enzime hidrolitice Acrozom Cap Nucleu Piesa intermediara - mitocondrii Coada – microtubuli propulsivi SPERMIATIE – eliberarea spermatozoizilor in lumenul tubului seminifer

  4. OVOGENEZA Celule germinale primordiale Mitoze Ovogonia Diploid, 2N Sinteza ADN Ovocit primar Diploid, 4N Meioza I ( 5 luni intrauterine ) Stadiu dormant ( profaza ) PUBERTATE Meioza I incheiata Ovocit secundar Haploid, 2N Primul globul polar Meioza II ( metafaza ) Ovocit definitiv 3 corpusculi polari Haploid, 1,1N OVUL – eliberat Fertilizatia

  5. 200 milioane spermatozoizi Cateva sute – ampula tubei uterine CAPACITATIA Etapa finala a maturarii spermiilor Enzime acrozom – zona pellucida Capacitatia artificiala – FERTILIZARE IN VITRO Foliculi primari 7 milioane 5 luni fetale 700 000 la nastere la pubertate ?

  6. CICLUL MENSTRUAL Secretii hormonale ciclice LUNARE HIPOTALAMUS GnRH HIPOFIZA – gonadotropine FSH si LH OVARE

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