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Joint Diseases 1

Joint Diseases 1. 5 types of joint disease ​Traumatic ​ synovitis , torn meniscus, osteochondral fracture (loose body in joint ) ​Infectious ​Septic arthritis: e.g. pus in joint, gonococcal arthritis (in young people). Degenerative: Osteoarthritis

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Joint Diseases 1

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  1. Joint Diseases 1

  2. 5 types of joint disease • ​Traumatic • ​synovitis, torn meniscus, osteochondral fracture (loose body in joint) • ​Infectious • ​Septic arthritis: e.g. pus in joint, gonococcal arthritis (in young people)

  3. Degenerative: Osteoarthritis • ​- failure of the articular cartilage • ​- joint space narrowing, higher density bone, bone growths (osteophytes) in response to cartilage loss, subchondral cysts • ​- most common joint disease, of varying severity.

  4. ​- Affects older people, weight bearing joints (hip, knee, spine), pain/stiffness/deformity, insidious onset relentless progress • ​- Primary (familial with overuse contributory) vs. secondary (old fracture or osteonecrosis) • ​- Treatment; total joint replacement (e.g. hip and knee).

  5. Rheumatic • ​Rheumatoid arthritis • ​- onset in 20-30s, women>men, subluxation of hands, systemic disease with synovitis (pannus) • ​- (compare to OA: affects elderly, men>women, weight-bearing joints, failure of articular cartilage).

  6. ​Ankylosingspondylitis: sacroiliac and spine fusion, HLA-B27 • ​Lupus, psoriasis, inflammatory bowel disease: polyarthritis.

  7. Metabolic • ​Gout: uric acid crystals, big toe, radiolucent, hyperuricemia, tophi • ​Pseudogout: calcium pyrophosphate deposition • ​Ochronosis: homogentisic acid deposition from defective Tyr and Phemetabolism.

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