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Tissues: The living fabric

Tissues: The living fabric. Ch 4 b Connective Tissue. First. Let’s review Epithelial tissue. What type is this?. Simple cuboidal epithelium. What type is this?. Simple cuboidal epithelium. What type is this?. Transitional epithelium. What type is this?. Transitional epithelium.

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Tissues: The living fabric

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  1. Tissues: The living fabric Ch 4 b Connective Tissue

  2. First Let’s review Epithelial tissue

  3. What type is this?

  4. Simple cuboidal epithelium

  5. What type is this?

  6. Simple cuboidal epithelium

  7. What type is this?

  8. Transitional epithelium

  9. What type is this?

  10. Transitional epithelium

  11. What type is this?

  12. Pseudostratified epithelium

  13. Pseudostratified epithelium What is this called?

  14. Pseudostratified epithelium What is this called? Cilia!

  15. What type is this?

  16. Stratified squamous epithelium

  17. What tissue is this?

  18. What type is this?

  19. Simple columnar epithelial tissue

  20. Connective Tissue

  21. Connective Tissue • Found throughout the body • Most abundant and most widely distributed

  22. Connective Tissue • Four Main classes • Connective tissue proper • Includes fat and fibrous tissue of ligaments • Cartilage • Bone • Blood

  23. Functions of Connective Tissue • Binding and support • Protection • Insulation • Transportation • blood

  24. Characteristics of Connective Tissue • Connective tissues have: • Common origin • Arise from Mesenchyme (an embryonic tissue) • Varying degrees of vascularity • From avascular to rich in blood vessels

  25. Characteristics of Connective Tissue • Has large amounts of nonliving extracellular matrix, consisting of ground substance and fibers

  26. Structural Elements of Connective Tissue • Has 3 main elements: • 1. Ground substance – unstructured material that fills the space between cells • 2. Fibers – collagen, elastic, or reticular

  27. Structural Elements of Connective Tissue • Has 3 main elements: • 3. Cells – fibroblasts, chondroblasts, osteoblasts, and hematopoietic stem cells

  28. Structural Elements of Connective Tissue • Ground substance and fibers make up the matrix

  29. Ground Substance • Functions as a molecular sieve through which nutrients diffuse between blood capillaries and cells Proteoglycan Structure

  30. Ground Substance • Composed of: • Interstitial (tissue) fluid • Adhesion proteins– serves as the glue • Proteoglycans – (protein core with glycosaminoglycans (GAGs) attached • Traps water

  31. Fibers – 3 types • Collagen – • Strongest, most abundant; • tough and provides high tensile strength • (stronger than steel fibers the same size) • Glistening white appearance – called white fibers

  32. Fibers • Elastic – • long, thin fibers • form branching network • allows for stretch • Contains rubber-like protein called elastin • Appear yellow so sometimes called yellow fibers

  33. Fibers • Reticular – • branched collagenous fibers • form delicate networks • Abundant where connective tissue abuts other tissue types • Basement membrane of epithelial • Form nets around capillaries

  34. CellsImmature and Mature forms • Actively mitotic immature cells that secrete ground substance and fibers in their particular matrix

  35. CellsImmature and Mature forms • Fibroblasts – connective tissue proper • Chondroblasts – cartilage • Osteoblasts – bone • Hematopoietic stem cells – blood

  36. Cells • Once matrix is synthesized, the blast cells mature into less active cells (indicated by the suffix –cyte) • Hematopoietic stem cells are always actively mitotic • Other cell types in connective tissue include White blood cells, plasma cells, macrophages, and mast cells

  37. Types of Connective Tissue

  38. Connective Tissue: Embryonic • Mesenchyme – embryonic connective tissue • Gel-like ground substance with fibers and star-shaped mesenchymal cells • Gives rise to all other connective tissues • Found in the embryo

  39. Connective Tissue: Embryonic Figure 4.8a

  40. Connective Tissue Proper • 2 subclasses • Loose connective tissue • Areolar, adipose, and reticular • Dense connective tissue • Dense regular, dense irregular, and elastic

  41. Connective Tissue Proper: Loose • Areolar connective tissue • Gel-like matrix with all three connective tissue fibers • Fibroblasts, macrophages, mast cells, and some white blood cells • Wraps and cushions organs • Widely distributed throughout the body

  42. Areolar Connective Tissue Figure 4.8b

  43. Connective Tissue Proper: Loose • Adipose connective tissue • Matrix similar to areolar connective tissue with closely packed adipocytes (fat cells) • Reserves food stores, insulates against heat loss, and supports and protects

  44. Connective Tissue Proper: Loose • Adipose connective tissue • Found under skin, around kidneys, within abdomen, and in breasts • Local fat deposits serve nutrient needs of highly active organs

  45. Connective Tissue Proper: Loose • Adipose connective tissue • Abundant – • average person 18% of body weight is adipose • Chubby person body can be 50% adipose tissue

  46. Adipose Figure 4.8c

  47. Connective Tissue Proper: Loose • Reticular connective tissue • Loose ground substance with reticular fibers • Reticular cells that lie in a fiber network • Forms a soft internal skeleton, or stroma, that supports other cell types

  48. Connective Tissue Proper: Loose • Reticular connective tissue • Found in lymph nodes, bone marrow, and the spleen

  49. Reticular Connective Tissue Figure 4.8d

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