DNA Fingerprints & Blood Groups

DNA Fingerprints & Blood Groups NAME:????

Instructions: • Enter your name here: “Joe Bloggs” • Read over the case study of Susie Q and answer the questions that follow, you may make use of any notes or powerpoints. • You will type your answers on the powerpoint itself where there is a textbox/drawing box that allows you to. • Once you have completed all the answers, delete all the slides that have “DELETE SLIDE” on them, save the powerpoint and hand it in for marking. • Imagine you are a forensic scientist when answering the questions. • With many of the ethical questions remember that there is no BLACK or WHITE answers. In fact ethics is all about GREY areas, as long as you substantiate you answers with logic and informative knowledge. • Read the mark scheme to make sure you have not left any points out. GREY BLACK

These are the days of our lives… • You are a forensic detective and specialize in child custody cases. • Susie Q is a 32 year old single mother who is currently unemployed and living financially off her monthly child’s grant and a small savings account which she inherited from her mother. A year ago she fell pregnant again and now has given birth to a baby boy, Tok. Poppers Galore was Susie Q’s boyfriend at the time she fell pregnant, but left her after he suspected that she was seeing his best friend, Johnny B. Goode. Her relationship with Johnny B. Goode was intimate one night after she went to him for help after Poppers Galore came home drunk and hit her. She is determined to know who the father is as she cannot finance two children, and would appreciate some sort of financial support, which she is by law entitled too. • She proposes her case to you and you accept gladly because you know that both Poppers and Johnny are extremely wealthy businessmen who could easily help support a child.

Evidence No. 1 • After questioning the two men, you notice that they are quite similar in looks, however Johnny has blue eyes and Poppers has brown eyes. You then look up in your records and read that Susie Q has Brown eyes and Tok was born with blue eyes. Recalling back to your matric syllabus you remember that Brown eyes was a dominant trait (B) while blues eyes was a recessive trait (b). • Using just this phenotypic evidence explain why one cannot deduce who is likely to be the father, even though Tok and Johnny both have blue eyes. Make use of the monohybrid crosses to help explain your answer (4)

MONOHYBRID CROSSES: = Susie Q = Poppers = Johnny = Possible Tok’s Fill in genotypes and show potential crosses P1: X gametes F1: Evidence No. 1 Fill in information to help you start…. • Brown eyes (B) Blue eyes (b) Genotypes: Tok = Johnny = Susie Q = / Poppers = / ?? ?? ? ? ? ? ?? ?? ?? ??

MONOHYBRID CROSSES: = Susie Q = Poppers = Johnny = Possible Tok’s P1: X gametes F1: Evidence No. 1 Write your deduction here… ?? ?? ?? ? ? ? ? ?? ?? ?? ??

Evidence No. 2 • You then decide to do a blood test as you know that blood genes were used as the earliest form of genetic markers. After taking blood from both potential fathers, Susie Q and getting hospital records that show Tok’s blood type, the following genotypes were found: Susie Q (IA/i), Tok (Blood group A), Johnny (IA/i), Poppers (IA/IB). • Draw Punnet squares on the next slide to show the potential blood group genotypes of the offspring (click on the ???? to add text). (5) • Are you able to come to a conclusion now as to who the father is, why? (2) • Looking at the allele frequencies/ phenotypic ratios/percentages who would you say is more likely to be the father, and why? (4)

Evidence No 2.1 ?? ?? ?? ?? • Draw Punnet squares on this slide to show the potential blood group genotypes of the offspring (click on the ???? to add text). (5) ?? ???? ???? ???? ???? ?? ?? ???? ?? ???? ???? ???? ***To insert superscript, go to Format – Fonts - superscript

Evidence No. 2 • 2) Are you able to come to a conclusion now as to who the father is, why? (2) • Answer here… • Looking at the allele frequencies/ratios/percentages of the potential offspring would you say is more likely to be the father, and why? (4) • Answer here…

Evidence No. 3 • You eventually persuade the SAPS to grant you funding to have DNA profiles/fingerprints done on all involved in your case. After gaining consent from all parties involved you send blood samples off to the National Forensics Laboratory in Pretoria for DNA profiling using certain genetic markers. Two weeks later the results return and are shown below right: • Can you now deduce who the father of Tok is? Who is it? (1) • Out of all the procedures taken, which do you think is the most reliable and give two reasons to support your answer? (3) • Give advantages and disadvantages of DNA profiling/fingerprinting and using blood groups in paternity testing. (5) • Do you think that it is ethical for Susie Q to allow the SAPS to obtain Tok’s DNA profile even though in the long run Tok lives a good life as a result of this case? Give reasons to support your answer? Bullet your answer.(4) • “One can never prove paternity, one can only disprove paternity” discuss this statement using scientific thinking. (4)

Evidence No. 3 • Answer here… • Answer here… • Answer here…

Evidence No. 3 • Answer here… • Answer here…

Name: Set info: Mark Scheme

DNA Fingerprints & Blood Groups