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Lab-On-A-Chip

Lab-On-A-Chip. Dinah Callender , RN The Pennsylvania State University. Objectives . Describe the lab-on-a- chip Describe the hardware used in the trend Review Software Define Axioms Review Criteria Describe Advantages and Disadvantages. Objectives. Ethics and Legal issues

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Lab-On-A-Chip

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  1. Lab-On-A-Chip Dinah Callender, RN The Pennsylvania State University

  2. Objectives • Describe the lab-on-a- chip • Describe the hardware used in the trend • Review Software • Define Axioms • Review Criteria • Describe Advantages and Disadvantages

  3. Objectives • Ethics and Legal issues • Describe informatics nurse using the chip • Summarize the lab on a chip

  4. What is Lab-on-a-Chip • Instrument that integrates one or several laboratory functions • Only millimeters to centimeters in size

  5. What is a Lab- on-a-Chip • Few drops of blood needed to function • Invented to perform blood analyses

  6. Hardware used in Trend • Laptop or PDA • Semiconductor Chip • Special Camera • Handheld device controller

  7. Hardware • Semiconductor chip • Made of • Silicon • Glass • Plastic • Paper

  8. Software Some of the software used in the chips created by  Agilent Technologies  are: • Compliance solution • RNA Solution • Mass spectrometry software • 2100 Expert Software

  9. Software • 2100 Expert Software for the Agilent 2100 Bioanalyzer -offers powerful data evaluation tools for all available assays - automatic and manual integration - smear analysis and many assay-specific tool.

  10. Axiom • Axiom 1- meets goal of user • Axiom 2 the software allows for evaluation and correction • Axiom 3- needs to be determined.

  11. “Global Health”

  12. Clinical Information System • Designed to collect patient data • Improves care by making data accessible • Patient-focused

  13. Review Criteria • This is a clinical information system • Used by physicians, nurses, and pharmacist • Enables documentation • The Configuration utilized is point of care • Data standard used is Healthlevel 7 (HL7) • Disease and Procedure Classification System (Northrop Grumman, 2010)

  14. Review Criteria • Nursing practice standards classification scheme

  15. Advantages • A decrease or no human mistakes • Can find bacteria, viruses, and cancers • Can extract DNA from cells • Cost effective • Small amount of blood needed

  16. Disadvantages • Chip is new on the scene • Not yet mature • People may be reluctant

  17. Ethical and Legal Issues • Lab on a chip utilizes wireless communication • Utilizes expert systems to develop diagnoses • Raises concern about privacy and legal responsibility • Personal health information widely accessible

  18. Competencies Beginning nurse would be able to : • Retrieve information • obtains results from patient monitoring system • Understands lab on a chip’s limitations Experienced nurse • Troubleshoots problems • Places monitoring systems

  19. Competencies Informatics nurse specialist • Will provide training programs • Foresees impacts on staff and patients • Makes lab on a chip user friendly Informatics Innovator • Develops sample trials • Does advanced analysis

  20. Informatics Nurse • Provides the education on how to use the chip • Show ways to troubleshoot any problems • Research to create new knowledge • Utilizes tools to maintain data integrity

  21. Lab on a chip • A mini-lab on a polymer chip • Uses small volumes of blood/ fluid • Fluids moved by pressure through channels • Used for mixing, dilution, staining • Detection on single integrated systems

  22. References • Agilent Technologies.(July, 2009). 2100 Expert Software. Retrieved on March17,2010,from www.chem.agilent.com/enus/products/instruments/labonachip/2100bioanalyzer/smallrnaassay/ • CBC News (2009, Oct.7). Breast cancer ‘lab on a chip’ developed. Retrieved on March17,2010, fromhttp://www.cbc.ca/health/story/2009/10/07/breast-cancer-chip. • Northrop Grumman (2010). Clinical Information System. Retrieved on April 17, 2010, from http://www.is.northropgrumman.com/by_solution/health_it/markets/health_cis/index.html

  23. References • Insight:Lab on a chip (July 26, 2006). Nature. Retrieved on March 17, 2010, from http://www.nature.com/nature/journal/v442/n7101/full/442367a.html • Lab-on-a-chip. Retrieved March 17, 2010, from http://en.wikipedia.org/wiki/Lab-on-a-chip • Societal and Ethical Interactions with Nanotechnology (SEIN)-An Introduction (April, 2005). SOCIETY ETHICS_BAIRD VOGTTOSEND[1].Retrieved April 18,2010,from http://arxiv.org/ftp/physics/papers/0504/0504007.pdf

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