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Chapter 9 Circulatory system

Chapter 9 Circulatory system. ---Closed tubular system ---cardiovascular system ---Lymph vascular system. The cardiovascular S hHeart artery vein Capillary. Capillary 1) LM : endothelium: basement membrane: pPericyte: /flattened with processes /function: i. support

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Chapter 9 Circulatory system

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  1. Chapter 9 Circulatory system

  2. ---Closed tubular system ---cardiovascular system ---Lymph vascular system

  3. The cardiovascular S • hHeart artery vein Capillary

  4. Capillary • 1) LM: endothelium: basement membrane: • pPericyte: • /flattened with processes • /function: • i.support • ii. undifferentiated cell

  5. endothelial cell: 1. processes –microvilli-like, finger-liked 2. plasmalemmal vesicle • /transendothelial channel • /function: transport large molecules and storage of membrane (for enlarge, enlongated, pore-formed and microvilli) • M3. microtubule and microfilament

  6. EM: classification ①Continuous capillary: ---Structural feature: A. endothelial cell: -more plasmalemmal vesicles -tight junction B. basal lamina: complete ---Distribution: CT, MT, lung and CNS

  7. ② Fenestrated capillary ---Structural feature: A. endothelial cell: -have fenestrae or pore (60-80nm in D, with 4-6 nm diaphragm) B. basal lamina: complete ---Distribution: gastrointestinal tract, endocrine gland and renal glomerulus

  8. ③Sinusoid capillaries( enlarge capillary) ---Structural feature: A. endothelium: gap, pore B. basal lamina: incomplete or no( absent) ---Distribution: liver, spleen and bone marrow

  9. 3) Function: a.Selected permeability and exchange of material b.Synthesis (F VIII Rag, endothelin, ET and PGI2) c.Anti-blood coagulate

  10. Artery ---large A: aorta, pulmonary trunk ---medium-sized A: all named A, the diameter > 1mm(radial A, ulnar A) ---small A: 300um<D<1mm

  11. tunica intima • endothelium：（1）endothelial process • （2）plasmalemmal vesicle • 2. subendothelial layer • 3. internal elastic lamina • tunica media • large artery (elastic membrane), medium-sized and small artery ( circumferentially arranged smooth muscle) • tunica advantitia • Loose connective tissue LCT, external elastic lamina

  12. Medium-sized A – muscular A ---Tunica intima A. Endothelium B. Subendothelial layer: CT -collagenous F -elastic F -smooth muscle C. Internal elastic membrane: wave-liked, pink-colored band- elastin

  13. ---Tunica media: thickest layer A. Smooth muscle: 10-40 layers of, circularly B. Elastic F: produced by SM C. Collagenous F: produced by SM -

  14. ---Tunica adventitia: A. loose connective tissue B. external elastic M

  15. 2) Large A: elastic A ---Structural features: a.Tunica intima is thick, and internal elastic M is not prominant b.Tunica media: consists of 40-70 layers of elastic membrane, collagenous fiber and SM

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