1 / 62

Preventing Infectious Disease Transmission

Preventing Infectious Disease Transmission. Thomas P. Fuller ScD, CIH, MSPH, MBA Tech Environmental – Massachusetts Nurses Association. Transmission of Disease. Environmental viability, Exposure route, Exposure pathway, Infectious dose, Incubation, Organism size/mass/density,

august
Download Presentation

Preventing Infectious Disease Transmission

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript


  1. Preventing Infectious Disease Transmission Thomas P. Fuller ScD, CIH, MSPH, MBA Tech Environmental – Massachusetts Nurses Association

  2. Transmission of Disease • Environmental viability, • Exposure route, • Exposure pathway, • Infectious dose, • Incubation, • Organism size/mass/density, • Lethality, • Treatment, • Communicabilty, • Control.

  3. “Control of Hospital Infections-A Practical Handbook”G. Ayliffe (2000) • Infection Control Team • Physicians, ICNs, Management • ICN Activities • Surveillance of infections, • Rapid identification and investigation of outbreaks, • Advice on isolation of patients, • Development of policies and procedures to control the spread of infections, • Training staff, • Preparation of annual statistical reports of infection rates.

  4. Hospital IC Goals and Measures • Improve hand hygiene, • Increase environmental cleaning, • Improve equipment cleaning, • Expand contact precautions, • As measured by, • Increased soap use, • # of training sessions, • Reduced # of infections, and • Personnel accountability scorecards.

  5. Goals Did NOT Include: • Discussion of worker safety, • Environmental or personal monitoring for infectious agents, • Evaluation of disinfection or sterilization techniques of chemicals, • Use of engineering controls such as ventilation or filtration, • Selection and use of Personal Protective Equipment (PPE), • The expertise of an Industrial Hygienist.

  6. Injury and illness rate of 10.1 Greatly under reported due to difficulties in to documentation, job classification, poor categorization of activities, long latent periods {HIV, Hepatitis}, and large varieties of sources and symptoms. Healthcare Workers at Risk

  7. Existing TB, HIV, hepatitis, measles, smallpox Emerging New agents or strains (SARS, H5N1 flu, MRSA), New vectors (moving between species), New pathways, Possibly more infectious, Possibly more lethal, ‘Super Spreading Events’, Less understood (vaccines, treatment, transmission, viability). Occupational Threats to Naturally Occurring Infectious Agents

  8. SARS and Healthcare Workers • 774 deaths/>8,000 SARS cases worldwide (~9%), • Low infectivity, high severity, • Many cases hospital acquired (nosocomial), • 44 deaths/375 cases(~12% in Toronto), • 42% of SARS cases were healthcare workers Toronto (57% Vietnam) (Booth), • Other reported mortality rates range between 34-52%.

  9. Transmission may be via inhalation of aerosols or droplets, or mucous membrane contact with fomites or body fluids, Infection rate was directly proportional to time spent in the patients’ room and illness severity. SARS and Healthcare Workers

  10. SARS Hospital Management Shortcomings • Failure to track patient contact history, • Lack of healthcare worker surveillance, • Failure/availability of ventilation systems and personal protective equipment, • Failure to track visitor contacts, • Lack of communications and preparedness • Recognition of disease, perception of risk, understanding disease, inability to prevent spread.

  11. H5N1 Influenza Pandemic Threat

  12. Current WHO Phase of Pandemic Alert

  13. "It is only a matter of time before an avian flu virus -- most likely H5N1 -- acquires the ability to be transmitted from human to human, sparking the outbreak of human pandemic influenza" Dr. Lee Jong-Wook WHO Director-General November 7, 2005

  14. The Next Pandemic?

  15. H5N1 Fears • Worlds’ population is immunologically vulnerable, • A new strain for which there are no residual antibodies from previous seasonal influenza outbreaks, • An extremely virulent disease, • (52-55% mortality). (www.who.int)

  16. Industrial Hygiene • Misunderstood and underutilized, • IC is unaware of IH capabilities, • Sophisticated IH activities are performed by other departments with little understanding or knowledge of IH principles, • Decisions made based on outdated assumptions and poor understanding of IH concepts (e.g. aerosol physics), • Difficulty for IH principles an suggestions to be understood or accepted.

  17. IH Expertise • Aerosol/particle physics, • Ventilation design/operation, • Air filtration systems, • Exposure assessment and control, • Contamination control/decontamination (toxicology), • Risk assessment, • Personnel Protective Equipment, • Respiratory Protection, • Biological hazards, and • Air monitoring/sampling and analysis.

  18. Industrial Hygiene, defined: • Anticipation* • Recognition* • Evaluation • Control

  19. Evaluation • Historically very little monitoring of infectious agents is done in U.S., • Low germ loads led to the feeling that monitoring didn’t provide any useful information at such low levels, • As a result few hospitals maintain the equipment or expertise in airborne or surface monitoring for infectious agents, • Additionally, not a lot is known about how and what to monitor, viability, and what are acceptable (safe) concentrations.

  20. Air Sample Considerations • When to sample? • Commissioning, before occupancy = baseline, • Measure all parameters for ventilation assurance and cleanliness, • To provide comparison data for future operations, • Disease outbreak analysis • Measure all parameters with empahsis on source detection, • Surface and air content for dust and fungi, • Surveillance • Pressure is most important, • Air exchanges for purging, • Non viable particles to assess filtration efficiency, • Viable organisms.

  21. SAS Air Sampler

  22. Interpretation of microbiology Data • Rank order analysis • Lowest counts in the areas with best filtration • Comparison necessary with outdoor control • Qualitative analysis • Pathogen recovery • Temperature selectivity • Pathogens grow best at >35C • Filtration efficacy determined at 25C

  23. Surface Monitoring and Evaluation • Not historically done to a great extent in health care, • Very useful demonstration during the SARS outbreak to demonstrate transmission throughout the hosptial , • cfus per square cm.

  24. Control of Aerosols • Reduce generation at source, • Containment at the source, • Reduce survival in the environment, • General exhaust ventilation, • Local exhaust ventilation, • Ventilation filtration.

  25. Aerosols • Solid or liquid particles and the gas in which they are suspended. • Gas • Liquid • Fog, mist, spray, haze. • Solid • Dust, fume, smoke. • Solid or Liquid • Smog, cloud.

  26. Factors Affecting Aerosol Generation • Energy Input • Low = large particles • High = small particles. • Infectious Units • Organisms per unit • Volume of original suspension • Persistence – particle size.

  27. Aerosol Buildup in Ventilated Space • 30 air changes per hour required to maintain or reduce concentrations, • Highest concentrations are in work areas, • Breathing zone is within 3 feet of source.

  28. Filtration Systems • Reduce contaminates in the air from local or general exhausts, • Variety of efficiencies for aerosols and gases.

  29. Engineering Controls • Facility Design - isolation • Ventilation • Filtration • Chemicals, gases, irradiative (UV, IR, RF, microwave, heat) • Isolation • Security Systems ?

  30. Positive Pressure Room Control monitor corridor •positive pressure greater supply than exhaust air volume •pressure differential @ >2.5 Pascal's or 0.01"w.g. ideal at 0.03”wg or 8 Pascal’s-range from 2.5 to 8.0 Pa •clean to dirty airflow, Intended usage's: •monitoring •immune compromised patient rooms • sealed room, about 0.5 sq feet leakage •operating rooms •recirculate air back through filters •>12 air exchanges per hour • greater than 125 cfm airflow differential supply vs exhaust

  31. Negative Pressure Room for Airborne Infection Isolation monitor corridor •negative pressure greater exhaust than supply air volume •pressure differential @ 2.5 Pascal's or 0.01"w.g •sealed room, with about 0.5 sq. feet leakage •airflow differential >125 cfm •clean to dirty, airflow •monitoring •>12 air exchanges per hour new or 6 ac/hr renovation •exhaust to outside or HEPA filtered if recirculated Intended usage's: +procedure/treatment rooms +bronchoscopy rooms +autopsy +emergency rooms

  32. Ventilation Controls • % outdoor air, • ACH • Volume, direction, plena, • Evaluation • Frequency, acceptance criteria, IAQ, humidity, particulates, • Filtration, • Type, efficiency, testing, maintenance,

  33. Ventilation/Filtration Bio-Seal Damper – Butterfly type HEPA Filter Technology HEPA Filter Assembly Bio-Seal Damper – Dish type

  34. Monitors and alarms: HEPA Filters Airflow Velocity Building Exhaust Fans Primary Containment Periodic testing Patient isolation rooms Negative pressure labs Hospital ventilation and filtration systems Containment System Monitoring

  35. Establishing Baseline Information • Air quality • Non viable & viable particles • Ventilation • Air exchanges, filtration & pressure • Operational Practice • Preventative maintenance • Housekeeping • Visitation

  36. Policies/Plans/Programs/Procedures Oversight and Review Enforcement Access Control/Contact/Transport Training (simulated Labs, medical drills) Vaccination, patient screening and isolation, medical surveillance, prophylaxis and treatment, Cleaning, Disinfection, Sterilization. Administrative Controls

  37. Activities • Continually review infection rates and sources, • Track and trend infection data, • Develop programs and procedures, • Communicate issues and work to develop solutions, • Monitor systems and correct deficiencies.

  38. Source Management Essential for Airborne Infectious Disease Control • Patient sources need to be recognized and isolated, • Environmental sources need to be managed through training and procedural practice, • Healthcare facilities must be maintained, • New facility design should facilitate infection control measures.

  39. Barrier management •Solid versus plastic barriers •Short and long term •Framed or taped barriers •Ceilings and doors as barriers •Smoke and aerosol control •Pressure differential management

  40. Contamination Control • Not as well understood in health care as we might like to think (health physics, nuclear power), • Little actual experience of workers with real-time monitoring, • Little actual awareness of how agents are spread on surfaces or might physically move about, • Few measurement methods currently available, basically none in real-time!

  41. Contamination Control • Consists of making a “best guess” of where the agents are likely to be (get), • Often there is very little understanding on the part of the medical community of the environmental viability of known organisms, much less unknown ones! (SARS).

More Related