1 nm

1. Genetically Engineered Materials Science & Engineering Center Mehmet Sarikaya, University of Washington, DMR 0520567 ADSORPTION, DIFFUSION, AND SUPRAMOLECULAR ASSEMBLY OF GENETICALLY ENGINEERED GOLD BINDING PEPTIDES ON Au(111) • The molecular recognition of solids by peptides, so far unexplored until this work, has prime importance in rapidly growing interdisciplinary research at the biology/materials interface with wide ranging impact in nano- and bio technology, and materials in medicine. • Here we show adsorption and diffusion of a 42-amino-acid long engineered gold-binding peptide, 3rGBP1 - (MHGKTQATSGTIQS)3, leading to supramolecular assembly on Au(111). • Analogous to the well-established atomic-level heterostructures on semiconductor substrates, the basis of today’s microelectronics, fundamental observations of peptide-solid interactions here may well form the basis of peptide-based hybrid molecular technologies of the future. 1 nm C. So, C. Tamerler and M. Sarikaya, ACS Nano, 3, 1525, 2009; C. So, J. Kulp, E. Oren, H. Zaiere, C. Tamerler, J. S. Evans, M. Sarikaya, Angew Chem, Intl. Ed., 48, 5174, 2009. Supported by NSF via GEMSEC, MRSEC at UW (DMR-0520567). For more information, visit the Genetically Engineered Materials Science and Engineering Center at: http://depts.washington.edu/gemsec/