Hematology . Jan Bazner-Chandler CPNP, CNS, MSN, RN. Blood. Blood is the fluid of life Blood is composed of: Plasma RBC WBC Platelets. Plasma. Plasma consists of: 90% water. 10 % solutes: albumin, electrolytes and proteins.
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CPNP, CNS, MSN, RN
Average life cycle is 120 days.
The bones are continually producing new cells.
Platelets are irregularly-shaped, colorless bodies that are present in blood.
Their sticky surface lets them form clots to stop bleeding.
Bone marrow is the spongy substance found in the center of the bones.
Von Willebrand Disease – 1% of population – men or women – prolonged bleeding time
Normal platelet count: 150,000 to 400,000
Whaley & Wong Text
Stasis of blood with clumping of cell in the microcirculation, ischemia, and infarction
Microcytosis = small in size
Hypochromia = decrease hemoglobin
Poikilocytosis = abnormal shape
Poor prognosis / death within 1st year due to septicemia or
Neutophil less than 500
Platelet less than 20,000
Hemoglobin less than 7
Bone marrow reveals hypo-cellular and fatty marrow.
Loss of moro or startle reflex can indicate possible brain damage due to Kernicterus