Tuberculosis: P revious and Present Millennium . . TB before advent of chemotherapy TB in 1950 - 2000 Morbidity, Mortality & Elimination of TB . Censina R. Apap, Pulmonologist. Introducing Myself. Respiratory specialist since 1983 Working in the Netherlands since 1977
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Censina R. Apap,
Conservative, directed at relief of symptoms.
Sanatorium R/ introduced in Germany by Brehmer resulted in 25% sputum conversion within 6 mo. 50% of smear positive cases died of disease within 5 years.
Total patients 1026 152 347
No of deaths 565 131 288
From W.A. Griep
Active treatment gives an additional sputum conversion of 6%.
Lung resection only possible with required appropriate intratracheal anaesthetic techniques.Active R/ of TB.
-> transmission through cough /sneeze -> infection: early 5-10%, late in 5%.
-> result: recovery (possible morbidity) / death.
unless otherwise indicated.
Risk -> outbreak
INH = 5-10%, RMP rare