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Join the review session on cancers of the reproductive system with expert Ashkan Afshin. Learn about tumor development, genetic abnormalities, new cases, and risk factors for breast, prostate, and other cancers. True or false questions included.
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Cancers of the Reproductive System Review Session November 19, 2012
Ashkan Afshin, MD, MPH ScD Candidate, Department of Epidemiology ScD Candidate, Department of Global Health & Population Harvard School of Public Health Kresge Building, Room 913 677 Huntington Avenue Boston, Massachusetts 02115 Phone: (949) 235-6137 Email: aafshin@hsph.harvard.edu
Review Sessions • Format: • Q & A (20 min) • Discussing the questions received by email (10 min)
Questions Please send your questions or suggestions to: • Text Message: (949) 235-6137 • Email: aafshin@hsph.harvard.edu
Stages of Tumor Development A B C E D Weinberg RA. How cancer arises. Sci Am. 1996 Sep;275(3):62-70.
Stages of Tumor Development Weinberg RA. How cancer arises. Sci Am. 1996 Sep;275(3):62-70.
Genetic Abnormalities in Cancer Cells • Oncogenes • HER2 → Breast Cancer • Tumor Suppressor: • BRCA→ Breast Cancer
New cases of cancer in the US American Cancer Society. Cancer Facts & Figures 2012. Atlanta: American Cancer Society.
New cases of cancer in the US American Cancer Society. Cancer Facts & Figures 2012. Atlanta: American Cancer Society.
New cases of cancer in the US American Cancer Society. Cancer Facts & Figures 2012. Atlanta: American Cancer Society.
True or False? • Testicular cancer is the most common form of cancer in men 16-34 • Positive family history of the testicular cancer increases the risk of the cancer • Testicular cancers is more common in African American males. • Carcinoma in situ can sometimes progress to invasive cancer • Obese men show highest risk of testicular cancer
True or False? • Testicular cancer is the most common form of cancer in men 16-34 • Positive family history of the testicular cancer increases the risk of the cancer • Testicular cancers is more common in African American males. • Carcinoma in situ can sometimes progress to invasive cancer • Obese men show highest risk of testicular cancer
Race & Prostate Cancer Incidence Incidence Mortality Mortality World J Urol (2012) 30:195–200
Race & Prostate Cancer Incidence Incidence Mortality Mortality World J Urol (2012) 30:195–200
Diet & Prostate Cancer Risk Giovannucci et al. Int. J. Cancer: 121, 1571–1578 (2007) Wilson et al. J Natl Cancer Inst. 2011;103(11):876-84. Chan et al. J ClinOncol 23:8152-8160
Diet & Prostate Cancer Risk Giovannucci et al. Int. J. Cancer: 121, 1571–1578 (2007) Wilson et al. J Natl Cancer Inst. 2011;103(11):876-84. Chan et al. J ClinOncol 23:8152-8160
Breast Cancer Risk Factors • True or False? • Nulliparity • Early menarche • Early menopause • Postmenopausal hormone use • Older forms of birth control pills • Premenopausal obesity • Alcohol use
Breast Cancer Risk Factors • True or False? • Nulliparity • Early menarche • Early menopause • Postmenopausal hormone use • Older forms of birth control pills • Premenopausal obesity • Alcohol use
Race/Ethnicity and Breast Cancer American Cancer Society. BreastCancer Facts & Figures 2011-2012. Atlanta: American Cancer Society.
Race/Ethnicity and Breast Cancer American Cancer Society. BreastCancer Facts & Figures 2011-2012. Atlanta: American Cancer Society.
American Cancer Society. Global Cancer Facts & Figures 2nd Edition. Atlanta: American Cancer Society; 2011.
Endometrial Cancer Risk Factors • True or False: • Nulliparity, • Early menarche • Late Menopause • Obesity • Prior breast cancer treatment with tamoxifen • Polycystic ovarian syndrome (PCOS)
Endometrial Cancer Risk Factors • True or False: • Nulliparity, • Early menarche • Late Menopause • Obesity • Prior breast cancer treatment with tamoxifen • Polycystic ovarian syndrome (PCOS)
Obesity • Obesity is not a risk factor for: • Breast Cancer • Ovarian Cancer • Testicular Cancer • Prostate Cancer
Obesity • Obesity is not a risk factor for: • Breast Cancer • Ovarian Cancer • Testicular Cancer • Prostate Cancer