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Cancers of the Reproductive System Review Session. November 19, 2012. Ashkan Afshin, MD, MPH ScD Candidate, Department of Epidemiology ScD Candidate, Department of Global Health  & Population Harvard School of Public Health Kresge Building, Room 913 677 Huntington Avenue

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Presentation Transcript
slide2

Ashkan Afshin, MD, MPH

ScD Candidate, Department of Epidemiology

ScD Candidate, Department of Global Health & Population

Harvard School of Public Health

Kresge Building, Room 913

677 Huntington Avenue

Boston, Massachusetts 02115

Phone: (949) 235-6137

Email: aafshin@hsph.harvard.edu

review sessions
Review Sessions
  • Format:
    • Q & A (20 min)
    • Discussing the questions received by email (10 min)
questions
Questions

Please send your questions or suggestions to:

  • Text Message:  (949) 235-6137
  • Email: aafshin@hsph.harvard.edu
stages of tumor development
Stages of Tumor Development

A

B

C

E

D

Weinberg RA. How cancer arises. Sci Am. 1996 Sep;275(3):62-70.

stages of tumor development1
Stages of Tumor Development

Weinberg RA. How cancer arises. Sci Am. 1996 Sep;275(3):62-70.

genetic abnormalities in cancer cells1
Genetic Abnormalities in Cancer Cells
  • Oncogenes
    • HER2 → Breast Cancer
  • Tumor Suppressor:
    • BRCA→ Breast Cancer
new cases of cancer in the us
New cases of cancer in the US

American Cancer Society. Cancer Facts & Figures 2012. Atlanta: American Cancer Society.

new cases of cancer in the us1
New cases of cancer in the US

American Cancer Society. Cancer Facts & Figures 2012. Atlanta: American Cancer Society.

new cases of cancer in the us2
New cases of cancer in the US

American Cancer Society. Cancer Facts & Figures 2012. Atlanta: American Cancer Society.

true or false
True or False?
  • Testicular cancer is the most common form of cancer in men 16-34
  • Positive family history of the testicular cancer increases the risk of the cancer
  • Testicular cancers is more common in African American males.
  • Carcinoma in situ can sometimes progress to invasive cancer
  • Obese men show highest risk of testicular cancer
true or false1
True or False?
  • Testicular cancer is the most common form of cancer in men 16-34
  • Positive family history of the testicular cancer increases the risk of the cancer
  • Testicular cancers is more common in African American males.
  • Carcinoma in situ can sometimes progress to invasive cancer
  • Obese men show highest risk of testicular cancer
race prostate cancer
Race & Prostate Cancer

Incidence

Incidence

Mortality

Mortality

World J Urol (2012) 30:195–200

race prostate cancer1
Race & Prostate Cancer

Incidence

Incidence

Mortality

Mortality

World J Urol (2012) 30:195–200

diet prostate cancer risk
Diet & Prostate Cancer Risk

Giovannucci et al. Int. J. Cancer: 121, 1571–1578 (2007)

Wilson et al. J Natl Cancer Inst. 2011;103(11):876-84.

Chan et al. J ClinOncol 23:8152-8160

diet prostate cancer risk1
Diet & Prostate Cancer Risk

Giovannucci et al. Int. J. Cancer: 121, 1571–1578 (2007)

Wilson et al. J Natl Cancer Inst. 2011;103(11):876-84.

Chan et al. J ClinOncol 23:8152-8160

breast cancer risk factors
Breast Cancer Risk Factors
  • True or False?
    • Nulliparity
    • Early menarche
    • Early menopause
    • Postmenopausal hormone use
    • Older forms of birth control pills
    • Premenopausal obesity
    • Alcohol use
breast cancer risk factors1
Breast Cancer Risk Factors
  • True or False?
    • Nulliparity
    • Early menarche
    • Early menopause
    • Postmenopausal hormone use
    • Older forms of birth control pills
    • Premenopausal obesity
    • Alcohol use
slide25

Race/Ethnicity and Breast Cancer

American Cancer Society. BreastCancer Facts & Figures 2011-2012. Atlanta: American Cancer Society.

slide26

Race/Ethnicity and Breast Cancer

American Cancer Society. BreastCancer Facts & Figures 2011-2012. Atlanta: American Cancer Society.

slide27

American Cancer Society. Global Cancer Facts & Figures 2nd Edition. Atlanta: American Cancer Society; 2011.

endometrial cancer risk factors
Endometrial Cancer Risk Factors
  • True or False:
    • Nulliparity,
    • Early menarche
    • Late Menopause
    • Obesity
    • Prior breast cancer treatment with tamoxifen
    • Polycystic ovarian syndrome (PCOS)
endometrial cancer risk factors1
Endometrial Cancer Risk Factors
  • True or False:
    • Nulliparity,
    • Early menarche
    • Late Menopause
    • Obesity
    • Prior breast cancer treatment with tamoxifen
    • Polycystic ovarian syndrome (PCOS)
obesity
Obesity
  • Obesity is not a risk factor for:
    • Breast Cancer
    • Ovarian Cancer
    • Testicular Cancer
    • Prostate Cancer
obesity1
Obesity
  • Obesity is not a risk factor for:
    • Breast Cancer
    • Ovarian Cancer
    • Testicular Cancer
    • Prostate Cancer