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Hepatitis A: Epidemiology. Presentation Prepared by: David Spach, MD and Nina Kim, MD Last Updated: May 31, 2011. HEPATITIS A : EPIDEMIOLOGY. Incidence Data. HEPATITIS A : EPIDEMIOLOGY. Acute Hepatitis A: 2011 Case Definition.

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hepatitis a epidemiology

Hepatitis A: Epidemiology

Presentation Prepared by: David Spach, MD and Nina Kim, MDLast Updated: May 31, 2011

acute hepatitis a 2011 case definition
HEPATITIS A : EPIDEMIOLOGYAcute Hepatitis A: 2011 Case Definition
  • Clinical Case DefinitionAn acute illness with:(a) discrete onset of symptoms and(b) jaundice, dark urine, or elevated ALT levels (ALT > 200 IU/L)
  • Laboratory Criteria for DiagnosisImmunoglobulin (IgM) antibody to hepatitis A virus (anti-HAV) positive
  • Case ClassificationConfirmed: meets the clinical case definition and is laboratory confirmed
incidence of hepatitis a in u s 1980 2008
HEPATITIS A : EPIDEMIOLOGYIncidence of Hepatitis A in U.S., 1980-2008

Source: CDC Division of Viral Hepatitis. Statistics and Surveillance.

incidence of hepatitis a in u s 1980 20081
HEPATITIS A : EPIDEMIOLOGYIncidence of Hepatitis A in U.S., 1980-2008

Source: CDC Division of Viral Hepatitis. Statistics and Surveillance.

incidence of hepatitis a in u s 1980 20082
HEPATITIS A : EPIDEMIOLOGYIncidence of Hepatitis A in U.S., 1980-2008

Source: CDC Division of Viral Hepatitis. Statistics and Surveillance.

impact of hepatitis a vaccine on estimated total new hepatitis a infections in u s 1980 2008
HEPATITIS A : EPIDEMIOLOGYImpact of Hepatitis A Vaccine on Estimated Total New Hepatitis A Infections in U.S., 1980-2008

2006: ACIP Recommends Universal Childhood Immunization

1996: ACIP Recommends for High-Risk Groups

1999: ACIP Expands Recommendations

1995HAV Vaccine Licensed

Source: CDC Division of Viral Hepatitis. Statistics and Surveillance.

reported hepatitis a by age group and year united states 1990 2004
HEPATITIS A : EPIDEMIOLOGYReported Hepatitis A, by Age Group and Year, United States, 1990-2004

†ACIP = Advisory Committee for Immunization Practices

Source: ACIP. MMWR Recomm Rep. 2006;55(RR-7):1-23.

rate of hepatitis a by county in united states 1987 1997 and 2004
HEPATITIS A : EPIDEMIOLOGYRate* of Hepatitis A, by County in United States, 1987-1997 and 2004

*Rate per 100,000 population

National Notifiable Disease System

Source: ACIP. MMWR Recomm Rep. 2006;55(RR-7):1-23.

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HEPATITIS A : EPIDEMIOLOGYEmerging Infections Program, Hepatitis Surveillance Sites, 2005-2007Potential Source of Infection or Risk Factor for Hepatitis A in US

IDU = Injection drug useMSM: men who have sex with men

Source: Klevens RM, et al. Arch Intern Med. 2010;170:1811-8.

reported risk factors for hepatitis a virus infection
HEPATITIS A : EPIDEMIOLOGYReported Risk Factors for Hepatitis A Virus Infection

Percentage of Risk Factors Among Patients with Acute Hepatitis A Infection

Source: CDC. Hepatitis Surveillance Report No. 59;2004.

prevalence of antibody to hepatitis a virus by country 2006
HEPATITIS A : EPIDEMIOLOGYPrevalence of Antibody to Hepatitis A Virus, by Country, 2006

Source: ACIP. MMWR Recomm Rep. 2006;55(RR-7):1-23.