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This study investigates the interaction between HIV-1 virion proteins and splicing factors such as ASF/SF2, SC35, and 9G8. Analyze the impact of these interactions on viral replication and RNA splicing.
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A 0,20 0,15 VIRION CAp24 (ng/µl) HIV-1 HIV-1 + ASF/SF2 0,10 HIV-1 + SC35 HIV-1 + 9G8 0,05 0 1:0.5 1:1 1:3 1:0.5 1:1 1:3 1:0.5 1:1 1:3 B +ASF/SF2 +SC35 HIV-1 +9G8 Pr55Gag p48 aCAp24 p41 CAp24/p25 aRT p66 p51 aVpr gp160 aTMgp41 TMgp41 1 2 3 4