Hematopoietic System- 1 Bone Marrow Hematopoiesis. Linda F. Cunningham, MD January 2, 2003. Hematopoietic System Bone Marrow. Hematopoietic active marrow with stem cells, progenitor cells, and developing erythroblasts, myeloblasts, and megakaryoblasts (red marrow)
Linda F. Cunningham, MD
January 2, 2003
Rodak #76 Core Biopsy shows 50 % fat and 50 % hematopoietic tissue
Small amounts of myeloid tissue (myelos=marrow) is removed from bone cavity and examined under the microscope-
Bone marrow aspiration
Bone marrow biopsy
Bone Marrow Core Biopsy
Cellularity and the architecture
Bone Marrow Aspiration
Cytology and maturation
The red cell maturation sequence and significance of the change in red cell size and cytoplasmic color
Recognize the bone marrow response to anemia
Leukemia and Maturation of Leukocytosis
A 54 year old man has a neoplastic disorder that shows a peripheral blood leukocytosis with a predominance of mature neutrophils, few myelocytes, metamyelocytes, and promyelocytes. Myeloblasts are not identified What is the most likely diagnosis?
Peripheral blood smear. Identify this cell
This basophilic staining large cell is present in the peripheral blood of a patient appropriately treated for anemia. What is the most like cause for this coloration?
Which of the following hematologic evaluations is most likely to give useful information about the maturation and cytology of the erythroid and granulocytic series?