Progress of NVDAL BSL-3 Construction Enuh R.Djusa DVM,Ph.D. Jl.Raya Pembangunan, Gn. Sindur Bogor 16340
BACKGROUND • HPAI is still problem in southeast Asia countries including Indonesia • Vaccination is one of the strategy implemented beside Other strategies • NVDAL ensures the quality of the vaccines distributed in Indonesia. • BSL-3 is urgently needed to test zoonotic diseases vaccines such as AI,Rabies,Brucella, Anthrax, and others.
References Internasional Standard: • WHO Laboratory Biosafety Manual, 3rd edition 2004 (accessed online 2010)3 • OIE Manual of Diagnostic Tests and Vaccines for Terrestrial Animals (2008): Chapter 1.1.2: Biosafety and Biosecurity in the Veterinary Microbiological Laboratory and Animal Facilities (accessed online 2010)
BSL-3 Construction Phase • Conceptual design • Review process • Detailed design • Review process • Tender preparation • Approval • Call for tender • Tender evaluation and award • Construction and supervision (site inspections and meetings) • Contractual and payment support • Commissioning and testing • Selection and appointment of certifier • Certification • Hand-over • Cold and training operation • Hot operation • Post-commissioning observation (warranty issues)
Location of BSL-3 in NVDAL BSL-3 size : 15 x 24 sq.m.
BSL 3 Lay out BSL-3 lay out
Room Arrangement • BSL-3 laboratory equipped by BSC class IIA2, refrigerator, freezer, CO2 incubator, centrifuges etc. • Cabinet Laboratory-style ABSL-4: isolators (animal isolators and surgical isolator).
Corridor: connected all laboratories, changing room for male/female, Equipment maintenance (autoclave, dunk-tank, pass-box, Storage room. • Decontamination airlock for heavy equipment transfer. • Administration room