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Chapter 8

Chapter 8. The Central Nervous System. 8-1. Chapter 8 Outline CNS Embryonic Development Cerebrum Visualizing the Brain Functional Specializations of the Brain Learning & Memory Brain Structure & Function Spinal Cord Peripheral Nervous System. 8-2. CNS. 8-3. CNS.

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Chapter 8

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  1. Chapter 8 The Central Nervous System 8-1

  2. Chapter 8 Outline • CNS • Embryonic Development • Cerebrum • Visualizing the Brain • Functional Specializations of the Brain • Learning & Memory • Brain Structure & Function • Spinal Cord • Peripheral Nervous System 8-2

  3. CNS 8-3

  4. CNS • Consists of brain & spinal cord • Receives input from sensory neurons • Directs activity of motor neurons • Association neurons integrate sensory & motor activity • Perform learning & memory Fig 8.1 8-4

  5. CNS continued • CNS composed of gray & white matter • Gray matter consists of neuron bodies & dendrites • White matter (myelin) consists of axon tracts • Adult brain weighs 1.5kg • Contains 200 billion neurons • Receives 20% of blood flow to body 8-5

  6. Embryonic Development 8-6

  7. Embryonic Development continued Fig 8.4 • Telencephalon grows disproportionately forming hemispheres of cerebrum • Ventricles & central canal are remnants of hollow part of neural tube • Contain cerebral spinal fluid (CSF) 8-10

  8. Cerebrum 8-11

  9. Cerebrum Fig 8.5 • Is largest part of brain (80% of mass) • Is responsible for higher mental functions 8-12

  10. Cerebrum continued • Its right & left hemispheres are interconnected by tract of the corpus callosum Fig 8.1 8-13

  11. Cerebral Cortex • Is highly convoluted • An elevated fold is called a gyrus (pl. gyri) • A depressed grove is called a sulcus (pl. sulci) Fig 8.5 8-14

  12. Cerebral Cortex continued • Each hemisphere has 5 lobes: frontal, parietal, temporal, occipital & insula Fig 8.5 8-15

  13. Cerebral Cortex continued Fig 8.5 • Frontal lobe is separated from parietal by central sulcus • Precentral gyrus of frontal lobe is involved in motor control • Postcentral gyrus of parietal lobe receives sensory info from areas controlled by precentral gyrus Fig 8.7 8-16

  14. Cerebral Cortex continued Fig 8.7 8-17

  15. Cerebral Cortex continued • Temporal lobe contains auditory centers; receives sensory info from cochlea • Also links & processes auditory & visual info Fig 8.5 8-18

  16. Cerebral Cortex continued • Occipital lobe is responsible for vision & coordination of eye movements Fig 8.5 8-19

  17. Cerebral Cortex continued • Insula plays role in memory encoding • Integrates sensory info with visceral responses • Coordinates cardiovascular response to stress Fig 8.5 Insula lobe (under frontal & temporal) 8-20

  18. Visualizing the Brain 8-21

  19. Functional Specializations of the Brain 8-28

  20. Basal Nuclei (basal ganglia) • Are distinct masses of cell bodies located deep inside cerebrum • Function in control of voluntary movement Fig 8.12 8-29

  21. Cerebral Lateralization • Refers to specialization of each hemisphere for certain functions • Each cerebral hemisphere controls movement on opposite side of body • & receives sensory info from opposite side of body • Hemispheres communicate thru the corpus callosum (Fig 8.1) 8-30

  22. Cerebral Lateralization continued • Left hemisphere possesses language & analytical abilities • Right hemisphere best at visuospatial tasks Fig 8.14 8-31

  23. Language • Language areas of brain known mostly from aphasias • = speech & language disorders due to brain damage • Broca’s area necessary for speech • Wernicke’s area involved in language comprehension Fig 8.15 8-32

  24. Emotion & Motivation • Originate largely in hypothalamus & limbic system (shown in blue on Fig 8.16) • Include aggression, fear, feeding, sex, & goal-directed behaviors Fig 8.16 8-33

  25. Learning & Memory 8-34

  26. Memory • Involves a number of regions in brain • Amnesia (memory loss) studies reveal separate short- & long-term memory systems 8-35

  27. Memory continued • Hippocampus is critical for acquiring new memories • & consolidating short- into long-term memory • Amygdala is crucial for fear memories • Storage of memory is in cerebral hemispheres • Higher order processing & planning occur in prefrontal cortex Fig 8.16 Prefrontal cortex 8-36

  28. Brain Structures & their Functions 8-40

  29. Thalamus & Epithalamus • Are located at base of cerebral hemispheres • Thalamus is relay center thru which all sensory info (except olfactory) passes to cerebrum • & plays role in level of arousal • Epithalamus contains choroid plexus which secretes CSF • Also contains pineal gland which secretes melatonin • Involved in sleep cycle & seasonal reproduction Fig 8.20 8-41

  30. Hypothalamus Fig 8.21 • Is most important structure for homeostasis • Contains neural centers for hunger, thirst, body temperature • Regulates sleep, emotions, sexual arousal, anger, fear, pain, & pleasure • Controls hormone release from anterior pituitary • Produces ADH & oxytocin • Coordinates sympathetic & parasympathetic actions 8-42

  31. Pituitary Gland Fig 8.21 • Is divided into anterior & posterior lobes • Posterior pituitary stores & releases ADH (vasopressin) & oxytocin • Both made in hypothalamus & transported to pituitary • Hypothalamus produces releasing & inhibitinghormones that control anteriorpituitary hormones 8-43

  32. Circadian Rhythms • Are body's daily rhythms • Regulated by SCN (suprachiasmatic nucleus) of hypothalamus • The master clock • Adjusted daily by light from eyes • Controls pineal gland secretion of melatonin which regulates circadian rhythms 8-44

  33. Midbrain • Contains: • Superiorcolliculi -- involved in visual reflexes • Inferiorcolliculi -- relays for auditory info 8-45

  34. Midbrain continued • Rednucleus & substantianigra -- involved in motor coordination • S. nigra dopamine neurons degenerate in Parkinson’s • Mesolimbic dopamine neurons are involved in reward & addiction Fig 8.22 8-46

  35. Hindbrain • Contains pons, cerebellum & medulla Fig 8.20 cerebellum pons medulla 8-47

  36. Hindbrain - Pons Fig 8.23 • Contains several nuclei of cranial nerves • & 2 important respiratory control centers • Apneustic & pneumotaxic centers 8-48

  37. Hindbrain - Cerebellum • 2nd largest structure in brain • Receives input from proprioceptors (joint, tendon, & muscle receptors) • Involved in coordinating movements & motor learning Fig 8.20 cerebellum 8-49

  38. Hindbrain - Medulla Fig 8.23 • Contains all tracts that pass between brain & spinal cord • & many nuclei of cranial nerves • & several crucial centers for breathing & cardiovascular systems 8-50

  39. Reticular Formation Fig 8.23 • Is complex network of nuclei & fibers spanning medulla, pons, midbrain, thalamus, & hypothalamus • Functions as reticularactivatingsystem • Sets level of arousal of cerebral cortex to incoming sensory information 8-51

  40. Spinal Cord 8-52

  41. Spinal Cord Tracts • Sensory info from body travels to brain in ascending spinal tracts • Motor activity from brain travels to body in descending tracts 8-53

  42. Ascending Spinal Tracts • Ascending sensory tracts decussate (cross) so that brain hemispheres receive info from opposite side of body • Same for most motor tracts from brain Fig 8.24 8-54

  43. Descending Spinal Tracts • Are divided into 2 major groups: • Pyramidal or corticospinal tracts descend directly without synaptic interruption from cerebral cortex to spinal cord • Function in control of fine movements Fig 8.25 8-55

  44. Descending Spinal Tracts • Reticulospinal or extrapyramidal tracts descend with many synapses • Influence movement indirectly Fig 8.25 8-56

  45. Peripheral Nervous System 8-57

  46. Peripheral Nervous System (PNS) • Consists of nerves that exit from CNS & spinal cord, & their ganglia (= collection of cell bodies outside CNS) 8-58

  47. Cranial Nerves • Consist of 12 pairs of nerves • 2 pairs arise from neurons in forebrain • 10 pairs arise from midbrain & hindbrain neurons • Most are mixed nerves containing both sensory & motor fibers 8-59

  48. Spinal Nerves • Are mixed nerves that separate next to spinal cord into dorsal & ventral roots • Dorsal root composed of sensory fibers • Ventral root composed of motor fibers Fig 8.28 8-60

  49. Spinal Nerves continued • There are 31 pairs: • 8 cervical, • 12 thoracic, • 5 lumbar, • 5 sacral, & • 1 coccygeal Fig 8.27 8-61

  50. Reflex Arc • Is a simple sensory input, motor output circuit involving only peripheral nerves & spinal cord • Sometimes arc has an association neuron between sensory & motor neuron Fig 8.28 8-62

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