Chapter 10. Drug Therapy in Pediatric Patients. Pediatric Patients. All patients younger than16 years Respond differently to drugs than the rest of the population More sensitive to drugs than other patients are Show greater individual variation
Drug Therapy in Pediatric Patients
A, Plasma drug levels following IV injection. Dosage was adjusted for body weight. Note that
plasma levels remain above the minimum effective concentration (MEC) much longer in the
infant. B, Plasma drug levels following subQ injection. Dosage was adjusted for body weight.
Note that both the maximum drug level and the duration of action are greater in the infant.
Approximate dosage for a child =
Body surface area of the child × adult dose