Here are some common key facts about Methadone. Know about methadone history, uses, effects etc. Buy quality methadone container bottle online wholesale in Australia.
In this article, we are discussing five facts about methadone that you probably didn’t know. So here we go.
Where does methadone come from?
Methadone was created by chemists in Germany during World War II to replace it with scarcely available morphine that was then used as a painkiller. Once known as Dolophine, it was used as pain medication for surgical and cancer patients in the US in 1947.
In 1950, Methadone was first used for short-term use to minimize withdrawal symptoms among heroin and morphine addicts.
How Methadone is different from morphine?
Methadone is different from morphine in terms of half-life, cost and uses. Methadone is used in situations where current or former drug addicts need medication; this is because patients are not likely to become dependent on it.
Methadone is effective when taken orally and effects are likely to last for 24 - 36 hours.
How does methadone affect the body as an opiate?
Methadone is an addictive central nervous system depressant that produces analgesia or insensitivity to pain, sedation, slows down respiration, lowers blood pressure and cause nausea. The subjective effects following single doses for non-addicted individuals are similar to those noted after morphine or heroin use.
How a patient builds up tolerance to methadone
Tolerance refers to the body’s ability to develop counteracting and re-stabilizing effects against pain, nauseating, sedative, euphoric, respiratory, and cardiovascular effects.
However, no tolerance is developed to the drug’s ability to stave off withdrawal symptoms. Therefore, once an addict is stabilized on methadone s/he performs normally – physically and psychologically. In some patients, and at higher doses, methadone may help improve anxiety, as it is not effective as a potent mood elevator.
What are common side effects of methadone?
Some of the side effects of methadone include weight gain, constipation, increased intake of fluids, increased frequency of urination, tingling in the hands and feet, increased sweating, skin rash, nausea, and delayed ejaculation. These effects may be slight and temporary.
The severity of withdrawal symptoms depends upon a few factors like what the drug is, the dose given, duration of use, interval between doses, health of the patient etc. Common symptoms of abrupt withdrawal from methadone include insomnia, anxiety, hypertension, irritability, chills, excessive perspiration, “runny” nose and eyes, enlarged pupils, sore and aching joints, muscle spasms, abdominal cramps, nausea, and diarrhoea.
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