biokimia n.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
BIOKIMIA PowerPoint Presentation
Download Presentation
BIOKIMIA

Loading in 2 Seconds...

play fullscreen
1 / 41

BIOKIMIA - PowerPoint PPT Presentation


  • 319 Views
  • Uploaded on

BIOKIMIA. Osfar sjofjan Email : osofjan@yahoo.com Or osfarsjofjan@yahoo.co.id. Buku Acuan. Trudy McKee and James McKee. 2003. Biochemistry: The Molecular Basis of Life. Third edition. McGraw-Hill, Boston.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'BIOKIMIA' - thatcher-rylee


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
biokimia

BIOKIMIA

Osfar sjofjan

Email : osofjan@yahoo.com Or

osfarsjofjan@yahoo.co.id

buku acuan
Buku Acuan
  • Trudy McKee and James McKee. 2003. Biochemistry: The Molecular Basis of Life. Third edition. McGraw-Hill, Boston.
  • Lehninger, Nelson, & Cox. 1997. Principles of Biochemistry.2nd edition. Worth Publishers.
  • Albert L. Lehninger. 1995. Dasar-dasar Biokimia. (Alih bahasa: Maggy Thenawidjaja). Penerbit Erlangga, Jakarta.
  • David S. Page. 1995. Prinsip-prinsip Biokimia. Penerbit Unair, Surabaya.
  • Soeharsono. 1982. Biokimia I dan II. Gadjah Mada University Press, Yogyakarta.
tata tertib kuliah
Tata Tertib Kuliah
  • Tepatwaktu, toleransimaks. 15 menit
  • TidakBerisik
  • HP tidakdiaktifkan
  • Hadir minimal 80%
  • Pahambahasa Indonesia & Inggris
  • Baca salahsatu / duabukuacuan
  • KerjakanTugas, Mid, & Ujian
rpkps mtk biokimia
RPKPS MTK BIOKIMIA

Mtkiniakanmembahastentangselsebagai unit dasarkehidupan (hewandantanaman), pengertianmetabolisme, strukturdanfungsi protein danenim, bioenergetikadanmetabolismekarbohidratdanlemak, biosintesis protein danasam amino, strukturdanfungsidanreplikasimakromoolekulinformasigenetik, biokimiakomunikasiintraselulairdanekstraselulair, biosintesis mineral danvitain. AplikasiIlmubiokimiaternakmenyiasaiperubaannutrisidanlingkungansertastrategiproduksisusu, telurdandaingsertaolahannya.

tujuan perkuliahan
Tujuan Perkuliahan
  • Mengenalkan dan memahamkan bahasa biokimia : Kosakata (istilah dan struktur kimia), tatabahasa (reaksi-reaksi kimia), struktur kalimat (Jalur metabolisme) dan arti (keterkaitan metabolik)
filosofi pembelajaran
FilosofiPembelajaran
  • Menjelaskan, bukan mengindoktrinasi
  • Menunjukkan hal yang perlu diketahui dan yang tidak perlu diketahui
  • Menghargai pertanyaan tentang hal yang belum diketahui
  • Mempelajari semua hal adalah tidak mungkin, tetapi yang lebih penting adalah mengorganisir hal yang kita ketahui agar dapat digunakan
strategi perkuliahan praktikum
STRATEGI PERKULIAHAN / PRAKTIKUM
  • Metode perkuliahan akan banyak menggunakan ceramah dikombinasikan dengan metode diskusi dan tugas membuat makalah serta pengembangan softskill mahasiswa (komunikasi lisan, etika dan berpikir analitis)
strategi perkuliahan praktikum1
STRATEGI PERKULIAHAN / PRAKTIKUM
  • Berbagai instruksi instruksional akan digunakan dalam perkuliahan tersebut yaitu membuat tugas terstruktur / makalah topik perkuliahan, mahasiswa mencari bahan dengan referensi terbaru yang dilampirkan bersamaan tugas terstruktur / makalah yang dikumpulkan pada tengah dan akhir semester sebagai salah satu komponen bobot penilaian
tugas
TUGAS
  • Mahasiswa ditugaskan untuk membaca setiap bacaan perkuliahan sebelum perkuliahan dilaksanakan
  • Tugas materi perkuliahan berikutnya diberikan tiap akhir pertemuan kuliah sebelumnya
  • Tugas terstruktur berupa makalah dan dipresentasikan pada perkuliahan sesuai jadwal yang disepakati
  • Tugas praktikum terdiri laporan sementara dan laporan akhir praktikum. Laporan sementara dikumpulkan tiap akhir praktikum, sedangkan laporan akhir dikumpulkan setelah semua materi praktikum selesai dilaksanakan
kriteria penilaian
KRITERIA PENILAIAN
  • Nilai diberikan terhadap mahasiswa apabila telah memenuhi ketentuan kehadiran kuliah yaitu 80% bagi mahasiswa baru dan 80% bagi mahasiswa mengulang
  • KehadiranPraktikum 100 %
  • PembobotanPenilaian (A,B+ … E) dilakukan menggunakan acuan SesuaiBukuPedomanPendidikanFpt UB
monev mtk biokimia
MONEV MTK Biokimia
  • Kuiz / TugasTerstruktur : 10 %
  • UTS : 30 %
  • Praktikum : 30 %
  • UAS : 30 %
staf pengajar
Staf Pengajar
  • Prof. Dr. IrKusmartono
  • Prof. Dr. Ir. Suyadi, M.Agr.DSc. MS
  • Dr. Ir. OsfarSjofjan, M.Sc
  • Dr. Ir. GatotCiptadi, DESS
  • Dr. Ir. EkoWidodo, M.Agr.Sc. M.Sc
  • Dr. Ir. Marjuki, M.Sc
  • DedesArmeningtiyas, S.Pt. MP
  • ArthariniIrsyammawati, S.Pt. MP
  • AchadiahS.Pt. MP
  • RiniDwiWahyuni, S.Pt. MP
  • FirmanDjaya, S.Pt. MP
what is biochemistry
What is biochemistry?
  • Definition:
    • Webster’s dictionary: Bios = Greek, meaning “life” “The chemistry of living organisms; the chemistry of the processes incidental to, and characteristic of, life.”
    • WebNet dictionary: “Biochemistry is the organic chemistry of compounds and processes occuring in organisms; the effort to understand biology within the context of chemistry.“
what is biochemistry1
What is biochemistry?
  • Understanding biological forms and functions in chemical terms
  • Biochemistry aims to understand how the lifeless molecules interact to make the complexity and efficiency of the life phenomena and to explain the diverse forms of life in unifying chemical terms.
issues addressed by biochemistry
Issues addressed by biochemistry
  • What are the chemical and three-deminsional structure of biomolecules?
  • How do biomolecules interact with each other?
  • How does the cell synthesize and degrade biomolecules?
  • How is energy conserved and used by the cell?
  • What are the mechanisms for organizing biomolecules and coordinating their activities?
  • How is genetic information stored, transmitted, and expressed?
history of biochemistry
History of Biochemistry
  • First to reveal the chemical composition of living organisms.

The biologically most abundant elements are only minor constituents of the earth’s crust (which contains 47% O, 28% Si, 7.9% Al, 4.5% Fe, and 3.5% Ca).

The six principle

elements for life

are: C, H, N, O,

P, and S.

slide17

Most of the elements in living matter have relatively low atomic numbers; H, O, N and C are the lightest elements capable of forming one, two, three and four bonds, respectively.

The lightest elements form the

strongest bonds in general.

history of biochemistry1
History of Biochemistry
  • Then to identify the types of molecules found in living organisms.
  • Amino Acids
  • Nucleotides
  • Carbohydrates
  • Lipids
history of biochemistry2
History of Biochemistry
  • Then to understand how the biomolecules make life to be life.
relationship between biochemistry and other subjects
Relationship between Biochemistry and other subjects
  • Organic chemistry, which describes the properties of biomolecules.
  • Biophysics, which applies the techniques of physics to study the structures of biomolecules.
  • Medical research, which increasingly seeks to understand disease states in molecular terms.
  • Nutrition, which has illuminated metabolism by describing the dietary requirements for maintenance of health.
slide21

Relationship between Biochemistry and other subjects

  • Microbiology, which has shown that single-celled organisms and viruses are ideally suited for the elucidation of many metabolic pathways and regulatory mechanisms.
  • Physiology, which investigates life processes at the tissue and organism levels.
  • Cell biology, which describes the biochemical division of labor within a cell.
  • Genetics, which describes mechanisms that give a particular cell or organism its biochemical identity.
1 energy which it must know how to
(1) ENERGY, which it must know how to:

Life needs 3 things:

  • Extract
  • Transform
  • Utilize
2 simple molecules which it must know how to
(2) SIMPLE MOLECULES, which it must know how to:

Life needs 3 things:

  • Convert
  • Polymerize
  • Degrade
3 chemical mechanisms to
(3) CHEMICAL MECHANISMS, to:
  • Harness energy
  • Drive sequential chemical reactions
  • Synthesize & degrade macromolecules
  • Maintain a dynamic steady state
  • Self-assemble complex structures
  • Replicate accurately & efficiently
  • Maintain biochemical “order” vs outside
biochemical transformations fall into five main groups
Biochemical Transformations Fall into Five Main Groups
  • Group transfer reactions
  • Oxidation-reduction reactions
  • Rearrangements (isomerizations)
  • Cleavage reactions
  • Condensation reactions
biomolecules structure
Building block

Simple sugar

Amino acid

Nucleotide

Fatty acid

Anabolic

Catabolic

Biomolecules – Structure
  • Macromolecule
  • Polysaccharide
  • Protein (peptide)
  • RNA or DNA
  • Lipid
1 relative electronegativities of the two atoms
O 3.5

Cl 3.0

N 3.0

C 2.5

1. Relative electronegativities of the two atoms

Bond strength includes dependence on

High electronegativity = High affinity for electrons

  • P 2.1
  • H 2.1
  • Na 0.9
  • K 0.8
common bond strengths
Common Bond Strengths

Approx. Avg.

Triple: 820 kJ/mole

Double: 610 kJ/mole

Single: 350 kJ/mole

in summary
In summary…
  • Tetrahedral carbon has versatile bonding properties
  • Compounds with many atoms may exist in many isomeric forms
  • Interconversion requires breaking chemical bonds
  • Large molecules are built from small ones by making new chemical bonds