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DAIS: Baseline Lipid Characteristics

Chol. TG. 232. 531. 354. 155. 177. 77. 0. 0. DAIS: Baseline Lipid Characteristics. mg/dL. Placebo. Fenofibrate. p = 0.033. TC. TG. LDL-C. HDL-C. mean + SD. DAIS Investigators. Lancet 2001;357:905-910. DAIS: Mean Lipid Changes. 10 0 -10 -20 -30. Percent Change.

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DAIS: Baseline Lipid Characteristics

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  1. Chol TG 232 531 354 155 177 77 0 0 DAIS: Baseline Lipid Characteristics mg/dL Placebo Fenofibrate p = 0.033 TC TG LDL-C HDL-C mean + SD DAIS Investigators. Lancet 2001;357:905-910.

  2. DAIS: Mean Lipid Changes 10 0 -10 -20 -30 Percent Change Placebo Fenofibrate TC LDL-C HDL-C TG DAIS Investigators. Lancet 2001;357:905-910. Reprinted with permission from Elsevier Science.

  3. DAIS: Angiographic Changes from Baseline % change p = 0.029 p = 0.020 p = 0.171 mm mm 4.00 2.00 0.00 -0.10 -0.08 -0.06 -0.04 -0.02 0.00 -0.10 -0.08 -0.06 -0.04 -0.02 0.00 -40% -25% -42% Progression of CAD Minimum lumen diameter Percent Stenosis Mean Segment Diameter DAIS Investigators. Lancet 2001;357:905-910.

  4. DAIS: Combined Clinical Endpoints 25 20 15 10 5 0 Placebo -23%* Fenofibrate *DAIS was not powered to examine clinical events. Even though the results suggest a trend, they were not statistically significant Event Rate 50 38 * Number of participants with at least one clinical or interventional endpoint, including death, stroke, MI, CABG, PTCA and hospitalization for angina DAIS Investigators. Lancet 2001;357:905-910.

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