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Mountain West Research Consortium Clinical Translational Research – Infrastructure Network The Mountain West CTR-IN. Robert D. Langer, MD, MPH Principal Investigator Research Professor of Allied Health Sciences, UNLV
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Mountain West Research ConsortiumClinical Translational Research – Infrastructure NetworkThe Mountain West CTR-IN Robert D. Langer, MD, MPH Principal Investigator Research Professor of Allied Health Sciences, UNLV Associate Dean for Clinical and Translational Research and Professor of Family Medicine-Las Vegas, UNSOM NIGMS Award: 1U54GM104944-01A1
What is it? • $20 million 5 year NIH Grant under the IDeA Program • Involving 13 universities across the 7 IDeA states in the Mountain West Research Consortium
What are the 7 Mountain West states? Alaska Hawaii Idaho Montana Nevada New Mexico Wyoming
Support: to foster Clinical and Translational Research (CTR) according to NIH Definitions for Core Resources to facilitate the development of researchers moving into CTR BOOTSTRAP CTR ACROSS THE MOUNTAIN WEST
We will sink or swim based on the increase in “R-level” translational and clinical research that we achieve across the region over the next 4 years “a rising tide that … … lifts all ships.”
Who is in it? • UNLV [host] • UNR/UNSOM • U. Alaska – Anchorage • U. Alaska – Fairbanks • U. Hawaii – Manoa • Boise State U. • Idaho State U. • U. Idaho • Montana State U. • U. Montana • New Mexico State U. • U. New Mexico • U. Wyoming
What will it do? • Provide Pilot Grants of $40,000-$75,000/yr • Support Mini-Sabbatical and Visiting Scholar awards to build collaborations • Provide Mini-Grants for a variety of activities that can help build independent research • Provide infrastructure and services through Key Component Activities
Funding preference • Promising Early Career or New Investigators developing clinical or translational research programs • Established Investigators moving from bench to translational or clinical • Projects focused on health issues relevant to the region, including those in rural and vulnerable populations
What will it do? • Use an NIH-style approach to applications and funding • Model the processes that clinical and translational investigators need to master to compete successfully for NIH support
Key Component Activities (KCAs) • Education, Mentoring & Career Development KCA • Study Design & Biostatistics KCA • Pilot Grant KCA • Administrative KCA, including editorial support, award management, Annual Meeting
Education Mentoring Study Design Biostat Annual Meeting ALL AVAILABLE regardless of whether you’ve received a competitive award from the CTR-IN
What will it do? • Hold an Annual Meeting to share science, motivate, build collaborations, & conduct study business that will: • rotate across the 13 partner institutions • feature an annual research theme relevant to health in the region • bring together supported investigators, interested researchers from the region, key administrators from partners, external scientists, the regional biostat team, and senior project staff Second Annual Meeting at UNLV June 7 – 11, 2015 free registration, hotel rate ~ $100/night
What’s the current status? • Round 1 Pilot Grants: • 24 applications, 6 awarded • Round 1A Pilot Grants: • 63 applications, 14 awarded • Round 2 Pilot Grants • 97 applications, 15 awarded
What’s the current status? • Round 2 Pilot Grant RFA for 7/1/14 – 6/30/15: • Process moved entirely online • Letters of Intent with Abstacts were due 3/7/14 • 124 LOIs with Abstracts received • Invitations to submit were provided 3/14/14 • Applications were due 4/25/14 • Awards were announced 6/26/14^ via the Pilot Grant Application Portal
Visiting Scholars • Call for 02 Year open through 11/26/14 • Early Career or New Investigator status • $8,000 to $10,000 including 10% indirect • Investigator salary NOT allowed • Earliest start date 03/01/15 • Funds must be expended by 06/30/15 • Applications submitted online • Total funds available for all awards in 02 Year: $40,000 • Anticipate up to 5 Awards • Dependent on quality and budgets of applications received • 5 Applications and 5 Awards in the 01 Year • U Montana – to PG Awardee, U Hawaii, UNLV [3] – one to PG Awardee
Mini-Sabbaticals • One call for 02 Year -- open through 11/26/14 • Mid-Career or Established Investigator status • Up to $20,000 including 10% indirect • Earliest start date 03/01/15 • Funds must be expended by 06/30/15 • Applications submitted online • Total funds available for all awards in 02 Year: $80,000 • Anticipate up to 4 Awards • Dependent on quality of applications received • First offered in the 02 Year
Mini-Grants • Two calls for 02 Year – first open through 10/06/14 • Preferred uses: • acquisition of pilot data • analysis of existing data with a specific plan to publish • development of an intervention • development of a community-based collaboration • development of a new research collaboration between investigators at two or more institutions within the CTR-IN
Mini-Grants • Up to $10,000 direct costs, plus 10% indirect • Investigator salary NOT allowed • Earliest start date 12/01/14 • Second call deadline for 02 Year: 01/14/15 • Funds must be expended by 06/30/15 • Applications submitted online • Total funds available for all awards in 02 Year: $200,000 • Anticipate up to 20 Awards • Dependent on quality of applications received • First offered in the 02 Year
Round 3 Pilot Grants • One call for 03 Year – RFA end of January 2015 • Earliest start date 07/01/15 • Funds must be expended by 06/30/16 • Applications submitted online
Your First Call … Your Local Concierge http://ctrin.unlv.edu/?page_id=447
Your First Call Once You Decide to Submit a Proposal … Your Local Biostatistician http://ctrin.unlv.edu/?page_id=186
Senior Leadership • Administrative Core • Bob Langer, UNLV, PI • Jim Kenyon, UNR, Proj Coord • John Foreyt, UNSOM, Eval Dir • Pilot Grants • Curtis Noonan, UMT, Director • Bill Shuttleworth, UNM, Assoc Dir • Education & Mentoring • Jillian Inouye, UNLV, Director • Bruce Shiramizu, UH, Mentoring • Pope Moseley, UNM, Mentoring • Pat Alpert, UNLV, Assoc Dir, Educ • Merle Kataoki-Yahiro, UH, Educ • Craig Molgaard, UMT, Educ • Design, Epidemiology, Biostat • Pope Moseley, UNM, Director • Orrin Myers, UNM, Assoc Dir UNM CTSA: Richard Larson
website ctrin.unlv.edu NIGMS Award: 1U54GM104944-01A1
Mountain West CTR-IN Organizational Structure Governance and Membership AFFILIATION COLOR CODE UNLV UNR/UNSOM U. New Mexico U. Montana NIH Other partner Institutions Outside the 7 state region Steering Committee Robert Langer, MD, MPH, Principal Investigator Jim Kenyon, PhD, Project Coordinator, Partners John Foreyt, PhD, Project Coordinator, T&E Rafael Gorospe, MD, PhD, Project Officer Maria Canto, DDS, MS, MPH, Project Scientist U. of Nevada, Las Vegas - Host U. Alaska – Anchorage Montana State U. U. Alaska – Fairbanks U. of Montana U. of Hawaii U. of Nevada, Reno Boise State U. New Mexico State U. Idaho State U. U. of New Mexico U. of Idaho U. of Wyoming Principal Investigator Robert D. Langer, MD, MPH External Advisory Committee William T. Cefalu, MD, Chair Jill G. Joseph, MD, PhD, MPH, Co-Chair +6 other members from outside the region Internal Advisory Committee Carolyn Yucha, PhD, Co-Chair Thomas Schwenk, MD, Co-Chair VPRs of all 13 Partner Universities Concierge Network Executive Committee PI 2 Project Coordinators 3[4 with PI]KCADirectors CTSC Coordinator Admin KCA Robert Langer, MD, MPH, KCA Director Jim Kenyon, PhD, Project Coordinator CREMCaD KCA Jillian Inouye, PhD, KCA Director Education Unit Patricia Alpert, DrPH, Associate Director Mentoring Unit Bruce Shiramizu, MD, Associate Director Tracking & Evaluation Unit John Foreyt, PhD, Project Coordinator UNM CTSC Richard Larson, MD, Coordinator CTPG KCA Curtis Noonan, PhD, KCA Director William Shuttleworth, PhD, Associate Director CRDEB KCA Pope Moseley, MD, KCA Director Regional Biostatistician Network