characterizing and classifying viruses viroids and prions n.
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Characterizing and Classifying Viruses, Viroids, and Prions. Chapter 13. Comparing the size of a virus, a bacterium, and a eukaryotic cell. General Features of Viruses #1. Obligate Intracellular Parasites Very small (ultramicroscopic) Non-cellular Not Alive Protein Coat …Capsid

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general features of viruses 1
General Features of Viruses #1
  • Obligate Intracellular Parasites
  • Very small (ultramicroscopic)
  • Non-cellular
  • Not Alive
  • Protein Coat …Capsid
  • Envelopes (some viruses..not all)
general features of viruses 2
General Features of Viruses #2
  • Utilization of Host Cell Machinery
  • Host Range
  • Genome
    • DNA or RNA but NOT both
    • Single stranded or double stranded
  • Enzymes (Polymerases) (some viruses…not all)
virus replication video clip part1 5 basic steps for all viruses
Virus Replication (Video clip-part1)(5 Basic Steps for all viruses)
  • Adsorption
  • Penetration
  • Replication
  • Maturation
  • Release
lysogenic cycle video clip part 2
Lysogenic cycle video clip-part 2
  • Lysogeny
  • Prophage
  • Temperate virus
  • Lysogenic conversion
    • Corynebacterium diptheriae
the reproductive cycle of an enveloped virus
The reproductive cycle of an enveloped virus
  • Attachment (adsorption)
  • Entry and Uncoating
  • Viral replication and protein synthesis
  • Assembly (maturation)
  • Release
cancer
Cancer

Some viruses are oncogenic

  • Protooncogenes
  • Oncogenes
viroids
Viroids
  • Short pieces of “naked” RNA
  • No Protein coat
  • Only known to infect plants
  • Cadang Cadang disease
prions
Prions
  • Infectious proteins
  • No nucleic acid involved
  • Cause degenerative brain diseases
    • Scrapie in sheep
    • Mad Cow Disease
    • Creutzfeldt-Jakob Disease
    • CWD Chronic Wasting Disease in deer/elk
chronic wasting disease
Chronic Wasting Disease
  • Chronic Wasting Disease (CWD) is a transmissible neurological disease of deer and elk producing lesions in brains of infected animals. It is characterized by loss of body condition, behavioral abnormalities and death. CWD is classified as a transmissible spongiform encephalopathy (TSE), and is similar to mad cow disease and scrapie.
prion cwd
Prion: CWD
  • Chronic Wasting Disease

Chronic Wasting Disease Among Free-Ranging Cervids by County,United States, January 2007

cwd in iowa not yet
CWD in Iowa???...Not Yet!
  • Each season about 4,000 deer are tested…none positive
  • Since 2002 over 20,000 deer tested without a positive