Animal Care Approvals. Animal Policy & Welfare Program Research Ethics Office University of Alberta. Animal Care Committees. Must function in each University or institution that uses animals. At large institutions, several ACCs may review research.
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Animal Policy & Welfare Program
Research Ethics Office
University of Alberta
“Protocols must be submitted to an appropriate review committee for all studies and courses which involve the use of vertebrates and some invertebrates in Categories B through E. Cephalopods and some other higher invertebrates have nervous systems as well developed as in some vertebrates, and may therefore warrant inclusion in Category B, C, D, or E.”
- Canadian Council on Animal Care
Experiments on most invertebrates or on live isolates (does not require review by the Animal Care and Use Committee).
at necropsy or from the slaughterhouse.
Experiments which cause little or no discomfort
Experiments which cause minor stress or pain of
Such procedures should not cause significant changes in the animal's appearance, in physiological parameters such as respiratory or cardiac rate, or fecal or urinary output, or in social responses.
During or after Category C studies, animals must not show self-mutilation, anorexia, dehydration, hyperactivity, increased recumbency or dormancy, increased vocalization, aggressive-defensive behavior or demonstrate social withdrawal and self-isolation.
Experiments which cause moderate to severe distress or discomfort.
Procedures used in Category D studies should not cause prolonged or severe clinical distress.
ANIMALS MUST NOT REACH
A MORIBUND STATE,
NOR DIE UNATTENDED.
According to University Animal Policy and Welfare Committee (UAPWC) policy, procedures which cause severe pain near, at, or above the pain tolerance threshold of unanesthetized conscious animals are not permitted.
1. Full approval (best option)
2. Major revisions required
3. Minor revisions required
4. Defer decision to a later date
Issued with all applicable funding sources specified.
The following are accepted by email:
When funds are available but the animal work is scheduled for a future date:
1. Complete the Application for a Release of Funds Agreement.2. Submit the application to the Research Ethics Office (REO) and if approved, a Release of Funds Agreement will be forwarded to the PI for signature.3. Once the signed agreement has been returned to REO the Research Services Office will be advised that the PI can be given access to funding referenced in the agreement.
NO ANIMAL WORK CAN BEGIN WITHOUT AN AUP APPROVAL.
I. Animal Ethics Policy
A. Administration of Animal Research Procedure (Roles and Responsibilities)
B. Animal Care & Use Committee Appeal Procedure
C. Animal Care & Use Committee Scientific & Pedagogic Merit Review Procedure
D. Animal Ethics Review Procedure
E. Animal Euthanasia Procedure
F. Animal Maintenance: Special Requests for Alternate Animal Holding/Housing Procedure
II. Animal User Training Policy
Principles of Laboratory Animal Science & Ethics
Core Topics Include:
Animal Care Mandate, Biosafety, Biosecurity, Introduction to Pain Management, Legislation and Compliance, Non-Experimental Variables, Occupational Health & Safety and the Three Rs
*All Principal Investigators and their personnel are required to participate.
Species-Specific or Procedure-Specific
Animal Handling Courses:
Cat, guinea pig, mouse, rabbit, rat, summer rabbit/rat, plus aseptic techniques, necropsy and individual techniques.
* The Research Ethics Office (REO) maintains the database for training / certifications for both Part 1 and Part 2 courses.