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Protein Synthesis

Protein Synthesis. Define- building amino acids into proteins. Transcription- the code on the DNA is transferred to the RNA T A C C G G C T A T A T A G C G A A A T G G C C G A T A T A T C G C T T T A C C G G C T A T A T A G C G A A

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Protein Synthesis

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  1. Protein Synthesis Define- building aminoacids into proteins. • Transcription- the code on the DNA is transferred to the RNA • T A C C G G C T A T A T A G C G A A • A T G G C C G A T A T A T C G C T T • T A C C G G C T A T A T A G C G A A • A U G G C C G A U A U A U C G C U U DNA DNA mRNA

  2. 2. The mRNA then leaves the nucleus and attaches to the ribosome in the cytoplasm • A U G G C C G A U A U A U C G C U U mRNA Ribosome

  3. CGG CGG UAC CUA CUA CUA UAC 3. Aminoacids in the cytoplasm are picked up by specific tRNA molecules Alanine Alanine Methionine Aspartic Acid Aspartic Acid

  4. Alanine CGG CGG Methionine UAC CUA CUA CUA UAC 3. Aminoacids in the cytoplasm are picked up by specific tRNA molecules Alanine Methionine Aspartic Acid Aspartic Acid

  5. Alanine CGG CGG Methionine UAC Aspartic Acid CUA CUA CUA UAC 3. Aminoacids in the cytoplasm are picked up by specific tRNA molecules Alanine Methionine Aspartic Acid Aspartic Acid

  6. Alanine CGG Methionine UAC 4. The tRNA molecules then bring the aa’s to the ribosome in the correct order as designated by the mRNA A U G G C C G A U A U A U C G C U U mRNA Ribosome

  7. Alanine CGG Methionine CUA UAC 5. Translation- the aa’s from each tRNA attach to one another at the ribosome mRNA A U G G C C G A U A U A U C G C U U Ribosome

  8. Alanine CGG Methionine Aspartic Acid CUA UAC 5. Translation- the aa’s from each tRNA attach to one another at the ribosome mRNA A U G G C C G A U A U A U C G C U U Ribosome

  9. Alanine Methionine 6. The tRNA molecules leave the aa’s and go back to the cytoplasm A U G G C C G A U A U A U C G C U U Ribosome 7. Once the aa’s are attached to one another, the ribosome releases this protein into the cytoplasm

  10. Alanine Methionine Aspartic Acid A U G G C C G A U A U A U C G C U U 6. The tRNA molecules leave the aa’s and go back to the cytoplasm Ribosome 7. Once the aa’s are attached to one another, the ribosome releases this protein into the cytoplasm

  11. Alanine Methionine Aspartic Acid Isoleucine A U G G C C G A U A U A U C G C U U 6. The tRNA molecules leave the aa’s and go back to the cytoplasm Ribosome 7. Once the aa’s are attached to one another, the ribosome releases this protein into the cytoplasm

  12. Alanine Methionine Aspartic Acid Isoleucine Serine A U G G C C G A U A U A U C G C U U 6. The tRNA molecules leave the aa’s and go back to the cytoplasm Ribosome 7. Once the aa’s are attached to one another, the ribosome releases this protein into the cytoplasm

  13. Alanine Methionine Aspartic Acid Isoleucine Serine Leucine A U G G C C G A U A U A U C G C U U Ribosome 6. The tRNA molecules leave the aa’s and go back to the cytoplasm 7. Once the aa’s are attached to one another, the ribosome releases this protein into the cytoplasm

  14. Review it! • 500 x 3 = 1500 pairs • 43 = 64 • AUG-UUA-AAG-CUG-CAG-CAG-UAU-CUU-CUC-CCC • met-leu-lys-leu-glu-glu-tyr-leu-leu-pro • UGG (mRNA) ACC (DNA) • 6 • CGU-CGC-CGA-CGG-AGA-AGG • ATG –TAC- CGT- GTC- CAG- CAC- TTG -GGC -ACG • AUG –UAC-CGU-GUC-CAG –CAC- UUG -GGC -ACG met-tyr-arg-val-glu-his-leu-gly-thr

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