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Transport. Blood. Blood and Blood Cells. Whole blood is slightly heavier and three to four times more viscous than water. A blood sample is usually about 45% cells by volume. Hematocrit - % of cells contained in a blood sample. Blood Cells. Most blood cells are red cells

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Transport

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  1. Transport Blood

  2. Blood and Blood Cells • Whole blood is slightly heavier and three to four times more viscous than water. • A blood sample is usually about 45% cells by volume. • Hematocrit - % of cells contained in a blood sample.

  3. Blood Cells • Most blood cells are red cells • The remaining 55% of a blood sample is clear, straw-colored liquid called plasma. • Plasma is a complex mixture of water, amino acids, proteins, carbohydrates, lipids, vitamins, hormones, electrolytes, and cellular wastes.

  4. Red Blood Cells • Also called erythrocytes. • Bioconcave discs in order to transport gases. • Each red blood cell is about 1/3 hemoglobin by volume. • Hemoglobin carries oxygen.

  5. Hemoglobin • When it combines with oxygen = oxyhemoglobin(bright red) • When oxygen is released = deoxyhemoglobin (darker)

  6. White Blood Cells • Also called leukocytes. • Function to protect against diseases. • Develop from hemocytoblasts in response to hormones. • Hormones fall into two groups: • Interleukins • Colony-stimulating factors (CSFs)

  7. Function of White Blood Cells • Protect against infection in various ways • Some phagocytize(eat) bacterial cells in the body • Others produce proteins(antibodies) that destroy or disable foreign particles

  8. Neutrophils and Monocytes • Most mobile and active phagocytic leukocytes. • Monocytes can engulf large objects • Neutrophils engulf same-sized or smaller objects. • Both contain many lysosomes

  9. Lymphocytes • Are important in immunity. • Produce antibodies that attack specific foreign substances that enter the body.

  10. White Blood Cell Counts • A total number of white blood cells exceeding 10, 000 per cubic mm of blood is called leukocytosis = an acute infection somewhere in the body. • Example: appendicitis.

  11. Leukopenia • A total white blood cell count of 5000 per cubic mm of blood. • Indicates typhoid fever, influenza, measles, mumps, chicken pox, AIDS, or poliomyelitis.

  12. DIFF • Differential White Blood Cell Count • Lists percentages of the types of leukocytes in a blood sample. • Useful because the relative proportions of white blood cells may change in a particular disease. • For example, the number of neutrophils usually increases during bacterial infections. The number of eosinophils increases during parasitic infections and allergic reactions. In AIDS, the number of a certain type of lymphocyte drops sharply.

  13. Blood Platelets • Also called thrombocytes. • Are not complete cells. • Arise from very large cells in red bone marrow called megakaryocytes. • Platelets help close breaks in damaged blood vessels and initiate formation of blood clots.

  14. Blood Plasma • We will go through this on Friday. • Assignment: • Pg. 325, 1-3, 8, 9, 10, 11, 12, • Critical thinking #1

  15. 5 Types of White Blood Cells Differ in size, nature of their cytoplasm, shape of their nucleus, and staining characteristics. • Neutrophil-lobed nucleus • Eosinophil-stains red • Basophil- stains deep blue • Monocyte- largest blood cells • Lymphocyte- large, round nucleus

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