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Enzymes

Enzymes. http://www.brainpop.com/health/nutrition/metabolism/. VOCAB!. What Are Enzymes?. Most enzymes are Proteins ( Different shapes and sizes) Act as Catalyst to accelerates a reaction Not permanently changed in the process. Enzymes. Are specific for what they will catalyze

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Enzymes

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  1. Enzymes http://www.brainpop.com/health/nutrition/metabolism/

  2. VOCAB!

  3. What Are Enzymes? • Most enzymes are Proteins (Different shapes and sizes) • Act as Catalyst to accelerates a reaction • Not permanently changed in the process

  4. Enzymes • Are specific for what they will catalyze • AreReusable • End in –ase -Sucrase -Lactase -Maltase

  5. How do enzymes Work? Enzymes work by weakening bonds which lowers activation energy Chemical Rxn’s will always EVENTUALLY happen…that do enzymes do?

  6. Enzymes Without Enzyme With Enzyme Free Energy Free energy of activation Reactants Products Progress of the reaction • Chemical Rxn’s need energy to occur • Catalyst lowers amt needed

  7. Enzyme-Substrate Complex Enzyme The substance (reactant) an enzyme acts on is the substrate Joins Substrate

  8. Active Site Enzyme • A restricted regionof an enzyme molecule which binds to the substrate. Active Site Substrate

  9. Induced Fit • A change in the shape of an enzyme’s active site • Induced by the substrate

  10. Induced Fit Active Site substrate Enzyme induced fit • A change in the configuration of an enzyme’s activesite. • Induced by the substrate.

  11. Enzymes are Exteremly picky Enzyme’s are like students (very picky) They may not work in certain conditions http://www.youtube.com/watch?v=--CtA-2SO7U

  12. pH on certain mammalian enzymes

  13. Inhibitors Inhibitors: causes the enzyme to change its shape, which in turn alters the active site. Noncompetitive Inhibitor Enzyme active site altered Substrate

  14. Summation: Enzymes • Mostly Proteins • Catalyze reactions  lower activation energy • Shape specific • No consumed in reactions • Are very specific… Pain in the tushmolecules • Temperature specific • pH specific • Also, They work better at different conditions. • What if you want to break milk down in you stomach faster, what could you do?

  15. Homework • Go to http://www.radiolab.org/2012/apr/02/holey-cow/ • Or just google the following “Holey cow, RadioLab” • Listen to the 15min radioshow on your computer or ipod. Few notes: Fistulaed cows Digestive tracts is a tube

  16. Questions to Answer! • 1) Give me feedback! What is your response to the radio show? Liked it? Boring? Explain? I would like to know. • 2) What did Beaumont first observe from the man who was shot? And why was this significant? • 3) Beaumont unknowingly removed enzymes from St. Martin. What did he find? • 4) How does this radio show connect to our class topic? • 4) How would you feel if Alexis St. Martin was your brother, how would you feel about people examining them the way Beaumont did? Consider the fact that this helped global technology and science studies and possibly influenced how we learn today. If I don’t see you tomorrow, this HW is due by EMAIL! (kevinsparaco@gmail.com) by 6pm Wednesday

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