ICSI is a procedure in which a single sperm is injected directly into an egg, thus sperm and egg interactions involved with normal fertilization are by-passed.
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ICSI is a procedure in which a single sperm is injected directly into an egg, thus sperm and egg interactions involved with normal fertilization are by-passed. ICSI technique is used together with IVF to overcome severe male infertility. ICSI is a micromanipulation technique that was introduced in the early 1990’s and has been successfully applied to the treatment of severe male infertility including suboptimal ejaculate samples, ejaculatory failure, obstructive and nonobstructive causes of azoospermia (complete absence of sperm).
IVF (In Vitro Fertilization) as well as ICSI (intracytoplasmic sperm injection) are assisted reproductive techniques However , most patients get foxed by these two terms and confuse one with the other. They aren’t too sure as to which one they should use and what its benefits will be.
Let’s look at each of these to understand what they involve ,and how they are different from each other:
The ICSI procedure involves stripping cells from around the egg and injecting a needle into the egg. A small percentage of eggs, often the less healthy eggs, may be damaged by these procedures and degenerate (5-10%). Sometimes eggs fail to fertilize normally or arrest at an early stage of development. ICSI pregnancy rates and live birth rates are similar to those achieved with IVF.
However, studies have shown that blastocyst formation is reduced compared to IVF cycles, particularly in cases of poor sperm motility and morphology. The arbitrary selection of sperm (rather than relying on the natural fertilization process) has potential for increased risks of genetically abnormal embryos and birth defects including infertility.
Despite general medical acceptance by the ART community, ICSI is still a relatively new procedure. Children born as the result of ICSI are still very young and have not yet reached an age to reproduce. There are possible unknown long-term effects including those that could occur in subsequent generations.