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López-Cortés LE. ECCMID 2013 abs. O119

1 of 2. Impact of clinical intervention bundle (CIB) on quality of care and mortality associated with Staphylococcus aureus bacteraemia (SAB).

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López-Cortés LE. ECCMID 2013 abs. O119

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  1. 1 of 2 Impact of clinical intervention bundle (CIB) on quality of care and mortality associated with Staphylococcus aureus bacteraemia (SAB) • Multi-centre, before-after-study: N=462 pts with Staphylococcus aureus bacteraemia (SAB) (excluding palliative care or death within first 72h of SAB) from 11 Spanish tertiary hospitals • CIB: Active consulting and follow-up of all SAB episodes by infectious disease specialist who provided written structured recommendations ≥3 days/week related to quality of care indicators • Outcome parameters: Management (quality of care) and outcome (mortality) of SAB + 6 months Clinical intervention bundle (CIB) based on 5 evidence-based quality of care indicators López-Cortés LE. ECCMID 2013 abs. O119

  2. 2 of 2 Impact of clinical intervention bundle (CIB) on quality of care and mortality associated with Staphylococcus aureus bacteraemia (SAB) Quality of care Mortality • Mortality during 6-month period: PRE: 27.6% vs INT: 23.6%; P=0.3 • Multivariable logistic regression(adjusted for age, Pitt score, type of acquisition, development of severe sepsis/septic shock): CIB is independent predictor of lower mortality: OR=0.46; 95% CI: 0.25-0.87; P=0.02 Application of a CIB for management of SAB may improve adherence to 3 quality of care indicators and decrease in-hospital mortality López-Cortés LE. ECCMID 2013 abs. O119

  3. 1 of 2 Outbreak of Elizabethkingia meningoseptica sepsis with meningitis in a well baby nursery Case report: N=3 newborns developing multi-resistant E. meningoseptica (Chryseobacterium meningosepticum) sepsis with meningitis in a well baby nursery (Taiwan; March-May 2012) Chen YJ. ECCMID 2013 abs. P957 Data from poster FU: follow-up; VP: ventriculoperitoneal

  4. 2 of 2 Outbreak of Elizabethkingia meningoseptica sepsis with meningitis in a well baby nursery Intervention: Plastic storage boxes, cleaned with tap water without sterilisation → replaced by stainless steel boxes with regular desinfection 2x/week→ no more E. meningoseptica infections since then An outbreak of E. meningoseptica sepsis and meningitis in a well baby nursery was possibly transmitted via contaminated facilities and was controlled after changing and sterilising them Chen YJ. ECCMID 2013 abs. P957 Data from poster

  5. 1 of 2 Risk of venous thromboembolism (VTE) after community-acquired bacteraemia (CAB) Population-based cohort study (Northern Denmark; 1992-2010): Study group: N=4,237 adult pts with CAB, confirmed by blood cultures on admission to medical ward (exclusion criteria: no recent hospital admission, no previous CAB or VTE) Control group: 10 non-hospitalised controls for each CAB patient, matched for age, sex and date of admission Dalager-Pedersen M. ECCMID 2013 abs. O287

  6. 2 of 2 Risk of venous thromboembolism (VTE) after community-acquired bacteraemia (CAB) • 90-day risk of VTE after CAB according to organism: Highest for Staphylococcus aureus: 3.62% • Adjusted relative risk (RR) for VTE after CAB: CAB is associated with an increased risk of first-time VTE 3 months and 1 year after diagnosis. However, the absolute risk of hospital-diagnosed VTE after CAB is low Dalager-Pedersen M. ECCMID 2013 abs. O287

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