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Spontaneous Damage to DNA

Spontaneous Damage to DNA. Examples of DNA Damage Induced by Radiation and Chemicals. Examples of DNA Damage Induced by Radiation and Chemicals. Direct Repair of Thymine Dimers. Not in humans. A metiltransferase é gasta nesta reacção. Base-Excision Repair.

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Spontaneous Damage to DNA

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  1. Spontaneous Damage to DNA

  2. Examples of DNA Damage Induced by Radiation and Chemicals

  3. Examples of DNA Damage Induced by Radiation and Chemicals

  4. Direct Repair of Thymine Dimers Not in humans

  5. A metiltransferase é gasta nesta reacção

  6. Base-Excision Repair

  7. Nucleotide-Excision Repair of Thymine Dimers

  8. Xeroderma pigmentosum • Autosomal recessive mutations in several complementation groups • Extreme sensitivity to sunlight • Predisposition to skin cancer (mean age of skin cancer = 8 yrs vs. 60 for normal population)

  9. Nucleotide excision repair - Energéticamente ineficiente

  10. Mismatch Repair in E. coli

  11. Teste de Ames para agentes mutagenicos

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