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Supplementary Figure 1

pbNK. CD56. CD3. dNK. CD56. CD3. Supplementary Figure 1. A. B. Notch 1. Notch 2. Notch 3. Notch 4. Primary NK. Notch 1. Notch 2. 500. 400. Notch 1. Notch 2. Notch 3. Notch 4. YTS. 400. 500. 500. 400. dNK. C. D. 6.6. 6.9. 6.4. 4.7. 4.7. 4.9. 15.8. 16.6. 13.3.

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Supplementary Figure 1

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  1. pbNK CD56 CD3 dNK CD56 CD3 Supplementary Figure 1 A B

  2. Notch 1 Notch 2 Notch 3 Notch 4 Primary NK Notch 1 Notch 2 500 400 Notch 1 Notch 2 Notch 3 Notch 4 YTS 400 500 500 400 dNK C D

  3. 6.6 6.9 6.4 4.7 4.7 4.9 15.8 16.6 13.3 Supplementary Figure 2 + IL-15 NO CYTOKINES + IL-12 Primary NK YTS JURKAT

  4. Supplementary Figure 3 Delta4-Ig A B Delta1-Ig Primary NK Primary NK YTS YTS NK92 NK-92 Jurkat Jurkat 0.5 μg 5 μg 2.5 μg 1 μg 0.1 μg 0.5 μg 5 μg 2.5 μg 1 μg 0.1 μg C Jagged1-Ig Primary NK YTS NK92 Jurkat 5g 2.5g 1g 0.5g 0.1 μg

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