Infrastructure and Methods to Support Real Time Biosurveillance. Kenneth D. Mandl, MD, MPH Children’s Hospital Boston Harvard Medical School. Category A agents. Anthrax ( Bacillus anthracis )• Botulism ( Clostridium botulinum toxin ) » Plague ( Yersinia pestis ) »
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Kenneth D. Mandl, MD, MPH
Children’s Hospital Boston
Harvard Medical School
(filoviruses[e.g., Ebola, Marburg] and arenaviruses [e.g., Lassa])
Traditional Disease Biosurveillance
Gain of 2
daysNeed for early detection
Syndromic Surveillance for Bioterrorism Following the Attacks on the World Trade Center --- New York City, 2001.
MMWR. 2002;51((Special Issue)):13-15.
Beta (Theta=-.02 Scale=95.5 a=1.44 b=5.57)The cluster