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THE ARTEPAL PROJECT

THE ARTEPAL PROJECT. TO IMPROVE THE AVAILIBILITY OF ACT. ARTEPAL 1/ THE PROJECT. PROJECT OF AEDES FOUNDATION Agreed and financed by E.U. on 3 years 3 sections: technology transfer, pregnant women, distribution

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THE ARTEPAL PROJECT

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  1. THE ARTEPAL PROJECT TO IMPROVE THE AVAILIBILITY OF ACT Nairobi03/2006

  2. ARTEPAL1/ THE PROJECT • PROJECT OF AEDES FOUNDATION • Agreed and financed by E.U. on 3 years • 3 sections: technology transfer, pregnant women, distribution • Oteci (senior-experts) in charge of technology transfer under control of a technical and scientific committee. • OBJECTIVE: IMPROVE AVAILIBILTY OF ACTs Nairobi03/2006

  3. ARTEPAL2/SITUATION • Evaluation of projectsin all the supply chain (plantations, extraction, pharma) and in different regions • Evaluation of extraction processes • Establishing connections between different partners • Support in GMPs at different levels in connection with WHO/pre-qualification. Nairobi03/2006

  4. ARTEPAL3/ FINDINGS • Numerous projects restarting basic studies available in the literature • Numerous plantation projects without available extraction unit. • Numerous projects without knowledge of the commercial possibilities and quality requirements • Numerous questions asked to WHO/RBM/MMSS and others Nairobi03/2006

  5. ARTEPAL3/FINDINGS • Since the meeting in Arusha, risks of inadaptation of demand and supply are increasing. • Quantities • Quality • Recommandation of WHO for only ACTs may deeply change the demand Nairobi03/2006

  6. ARTEPAL4/PROPOSAL S • WHO/RBM/MMSS with MSH/RPM Plus intend to produce a guide to API production covering : • Cultivation issues on artemisia annua: • Seeds: sourcing, quantities needed • Planting, growing conditions, climate… • Areas of cultivation and surfaces • Major issues, agricultural and financial • Average biomass and artemisini content Nairobi03/2006

  7. ARTEPAL4/PROPOSALS • Production of Artemisinin • Extraction units: • Where • Capacity, quantity and time of production • Kind pf process • Possibilities to extract other products • Constraints: technical, financial • Issues involved with respect to the quality of finished ACTs: • GAP • GMP • DMF… Nairobi03/2006

  8. ARTEPAL4/PROPOSALS • Main deliverable: • « Market analysis »of the current situation in terms of capacity, quality issues,.. • A guide for resources, contacts • Table or tool to estimate cultivation and extraction needs across the production chain. Nairobi03/2006

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