'Topo ii' presentation slideshows

Am J Surg Pathol Volume 31, Number 5, May 2007

The Expression of Transforming Growth Factor-a in Cirrhosis, Dysplastic Nodules, and Hepatocellular Carcinoma An Immunohistochemical Study of 70 Cases. Am J Surg Pathol Volume 31, Number 5, May 2007

641 views • 52 slides

Childhood Leukemia Causation

Childhood Leukemia Causation. By Terry Nordbrock, MPH student Mel & Enid Zuckerman College of Public Health Tucson, AZ December 2005. Overview of presentation. What is leukemia? What are the known causes in adults? What are the known causes in children? What are the causal mechanisms?

632 views • 48 slides

Study sponsored by Sanofi-Aventis Support from Genentech

Phase III Trial Comparing AC-T with AC-TH and with TCH in the Adjuvant Treatment of HER2 positive Early Breast Cancer Patients: Second Interim Efficacy Analysis.

568 views • 42 slides

In vivo DNA binding pattern of the Polycomb Txn Factor

In vivo DNA binding pattern of the Polycomb Txn Factor. What are the genes to which it binds? How does it affect these genes?. 3. What determines where it Binds??. Nitrogenous base. Sugar. Phosphate. 1. Evidence for the Double Helix. helical. 1. Fiber Diffraction data :

590 views • 41 slides

In vivo DNA binding pattern of the Polycomb Txn Factor

In vivo DNA binding pattern of the Polycomb Txn Factor. What are the genes to which it binds? How does it affect these genes?. 3. What determines where it Binds??. Nitrogenous base. Sugar. Phosphate. 1. Evidence for the Double Helix. helical. 1. Fiber Diffraction data :

585 views • 41 slides

Topoisomerase Type II Structures

556 views • 31 slides

excessive SMC growth within the vascular wall after trauma -proliferation -apoptosis -migration - accelerated matrix de

Intimal hyperplasia. excessive SMC growth within the vascular wall after trauma -proliferation -apoptosis -migration - accelerated matrix deposition major cause of failure of endovascular and vascular reconstructions so far very difficult to treat .

456 views • 27 slides

How does higher-order chromatin structure differ in normal and cancer cells?

NU-PS-OC Project 3 DNA information and organization at supranucleosomal scales: chromatin folding and higher-order structure, patterns of DNA replication initiation John F. Marko Northwestern University. How does higher-order chromatin structure differ in normal and cancer cells?.

270 views • 25 slides

TOPOISOMERASE INHIBITORS and ( Multidrug Resistance (MDR PHL 417

TOPOISOMERASE INHIBITORS and ( Multidrug Resistance (MDR PHL 417. Role of Topoisomerases (TOPO) TOPOISOMERASES induce TRANSIENT BREAK in single strand (TOPO I) and double stands (TOPO II) and RESEALING. Topoisomerase I : Swiveling DNA into 2 single strands which is important for

251 views • 18 slides

Granzyme B

Granzyme B. SIGMA-ALDRICH. Granzyme B

187 views • 2 slides

Plasma Membrane

Graphical Abstract. Plasma Membrane. Inhibition of ATPase domain of Hu-TopoII ? leads to DNA damage. (1,4-benzoquinone or 1,4-naphthoquinone , 1,2-naphthoquinone or 9,10-phenanthroquinone). Cytoplasm. TopoII ? -DNA complexes. Topo II cleaves DNA and religates using ATP. DNA DSBs.

138 views • 1 slides