'Sodium channels' presentation slideshows

Nervous system

906 views • 81 slides

Pesticides: Types and Modes of Action

Pesticides: Types and Modes of Action. ENY 3225 or ENY 5226. Learning Objectives. Learn and internalize definitions Be able to list the steps for each mode of action for the pesticide groups presented

1.45k views • 65 slides

Antiseizure Drugs

Antiseizure Drugs. By Bohlooli S, PhD School of Medicine, Ardabil University of Medical Sciences. Introduction. Approximately 1% of the world's population has epilepsy Epilepsy is a chronic disorder characterized by recurrent seizures

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Homeostasis and Animal behavior review

Homeostasis and Animal behavior review. Name that behavior. Ducklings learn to follow the first moving object they see after they hatch

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Voltage-gated Sodium Channels

Voltage-gated Sodium Channels. XuelianMa. Introduction. In1952 ? Hodgkin and Huxley demonstrated the role of sodium channels in action potential electrogenesis and predicted many of the properties of these channels

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Communication within the Nervous System Chapter 2

The cells that make us who we are How neurons communicate with one another. Communication within the Nervous System Chapter 2. The Cells That Make Us Who We Are. How many are there? Neurons : 100 billion Make up 10% of brain volume Glial cells : Many more! Make up 90% of brain volume

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Voltage-gated sodium channels

Voltage-gated sodium channels. Xiao Yu Institute of Physiology Shandong University, School of Medicine 2012-11-10. Sodium channel genes are latecomers to the 6TM Family. (Zakon HH, PNAS 2012). Sodium Channels - Structure.

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Current Therapy for Epilepsy

Current Therapy for Epilepsy . J. Layne Moore, MD, MPH Professor Neurology Wright State University Boonshoft School of Medicine. Epilepsy. A disease known from antiquity Initially thought to be from the attack of a spirit or demon

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Nervous System Review

Nervous System Review. Chapter 12, 13 & 14. Which Neuroglia cell is responsible for cleaning up around neurons?. Astrocytes Oligodendrocytes Microglia Ependymal cells . Which Neuroglia cell Produce Myelin sheaths in the CNS?. Astrocytes Oligodendrocytes Microglia Ependymal cells .

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Nerves, Hormones, & Homeostasis

Nerves, Hormones, & Homeostasis. http://ehumanbiofield.wikispaces.com/Neuron+Structure+NLL. http://www.youtube.com/watch?v=xRkPNwqm0mM. http://www.youtube.com/watch?v=lh4pdaWYu7A. http://www.biologyreference.com/Oc-Ph/Peripheral-Nervous-System.html. http://i-biology.net/.

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LECTURE 6: ACTION POTENTIAL INITIATION AND PROPAGATION

LECTURE 6: ACTION POTENTIAL INITIATION AND PROPAGATION. REQUIRED READING: Kandel text, Chapter 9. Action potential (AP) is a brief spike of strong membrane depolarization at a point along the axon caused by inward current flow

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Phases

Phases

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Biological Bases of Behaviour. Lecture 3: Brain Cells and Neural Communication

Biological Bases of Behaviour. Lecture 3: Brain Cells and Neural Communication. Learning Outcomes. At the end of this lecture you should be able to: 1 . Describe the key elements of a nerve cell (neuron). 2 . Describe the main support cells of the CNS.

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Transmission of Action Potentials

Transmission of Action Potentials. Miss Tagore Year 13 Biology. Lesson Starter. In the resting phase of an action potential, what type of protein in the cell membrane is active? The sodium potassium pump. (Sodium channels are closed as are the majority of potassium channels).

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Chapter 48 Neurons, Synapses, and Signaling

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Transmission of Nerve Impulses

Transmission of Nerve Impulses. Nerve Impulse. An electrical current, travels along dendrites or axons Ions move through voltage-gated channels Channels open/close in response to changes in electrical charge around them. Resting Membrane Potential.

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Na + channel blocker : Na + channel block depends on: HR Membrane potential

Na + channel blocker : Na + channel block depends on: HR Membrane potential Drug specific physiochemical characteristic- ? recovery Blockade of Na + channels results in: Threshold for excitability is increased (more current) Increase in pacing and defibrillation threshold

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LECTURE 12: MYELIN AND SALTATORY CONDUCTION

LECTURE 12: MYELIN AND SALTATORY CONDUCTION. REQUIRED READING: Kandel text, Pgs 22, 81-87. Myelin is an electrical insulator sheath wrapped around axons Oligodendrocytes produce myelin on CNS axons Schwann cells produce myelin on PNS axons

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Neuron Description and Nerve Impulses

Neuron Description and Nerve Impulses. Neuron: Cells of the nervous system specialized to transmit messages throughout the body.

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ion channel screening

Ion channels are pore-forming proteins that are located within the membrane of most cells and of many intracellular organelles. Their functions include maintaining a resting membrane potential, conducting action potentials and other electrical signals. They are characterized by their selective permeability - the ability to allow only certain sized/charged ions to pass through; thus playing vital roles in various physiological activities. These features make themselves become perfect targets in the process of novel drug development.

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