'Rna polymerase ii' presentation slideshows

1. Overview: The Flow of Genetic Information

1. Overview: The Flow of Genetic Information. The information content of DNA is in the form of specific sequences of nucleotides The DNA inherited by an organism leads to specific traits by dictating the synthesis of proteins

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Chapter 31

Chapter 31. Transcription and Regulation of Gene Expression to accompany Biochemistry, 2/e by Reginald Garrett and Charles Grisham.

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What does the word Promoter mean?

What does the word Promoter mean?. It is the place at which RNA Pol II binds. But the word is incorrectly used to describe Enhancers plus Promoter. Initiation by RNA Polymerase II. TFIID recognition site is TATAA. How often is this site found in the genome? 1/4 5.

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Selected topics in Transcription

Selected topics in Transcription. Nir London. Computational Biology Seminar 2006. Overview. Elongation Pause; Arrest Chromatin remodeling; Histones CTD Mediator Complex Mechanism model Composition and Interaction network Initiation Mechanism New findings. Elongation.

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L.O 3.33: The student is able to use representations and appropriate models to describe features of a cell signaling pa

L.O 3.33: The student is able to use representations and appropriate models to describe features of a cell signaling pathway. SP 1.4: The student can use representations and models to analyze solutions or solve problems qualitatively and quantitatively.

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CHAPTER 6 HOW CELLS READ THE GENOME: FROM DNA TO PROTEIN

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Review: RECOMB Satellite Workshop on Regulatory Genomics

Review: RECOMB Satellite Workshop on Regulatory Genomics. (Held March 26-27, 2004). Workshop Themes/Trends. More comprehensive evaluations of motif-detection algorithms Making more effective use of comparative mapping/ evolution data Models that explain rather than just describe

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Eukaryotic gene expression

Eukaryotic gene expression. Bacterial genes have a ground state that permits transcription Without CAP site or operator, the sigma subunit will locate a gene Eukaryotic genes require complex systems to turn them on

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Regulatory Motif Finding

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Transcription

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Comparative Genomics II : Functional comparisons

Comparative Genomics II : Functional comparisons. Caterino and Hayes, 2007. Overview. I. Comparing genome sequences Concepts and terminology Methods Whole-genome alignments Quantifying evolutionary conservation ( PhastCons , PhyloP , GERP) Identifying conserved elements

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Transcription

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Alternative splicing controls sex determination in Drosophila

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Host-Pathogen Strategies #1

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Transcription

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Three RNA polymerases in eukaryotes

Three RNA polymerases in eukaryotes. RNA polymerase I. Non-transcribed spacer. 1 promoter - 50% of a cell transcriptional activity - low sensitivity to a - amanitin Transcribe gene encoding the 45S precursor of rRNAs (18S, 5.8S, 28/26S rRNAs ). 5.8S. 5.8S. 18S. 18S. 28S. 28S.

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Transcription

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FIGURE 6.2. Synthesis of an RNA strand.

FIGURE 6.1. RNA contains the sugar ribose and the base uracil in place of deoxyribose and thymine. FIGURE 6.2. Synthesis of an RNA strand. FIGURE 6.3. Numbering on a DNA sequence.

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p300

PCAF. PCAF. Tat. Tat. Tat. Ac. Ac. Ac. Tat. 1. PCAF interacts with and acetylates Tat on lysine 28. 2. K28-acetylated Tat interacts with P-TEFb. P-TEFb. 3. P-TEFb/Tat complex binds TAR RNA. P-TEFb. 4. p300 acetylates Tat on lysine 50. RNA polymerase II. +1. p300. P.

241 views • 1 slides